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Title: Characterization and antimicrobial activity of Streptomyces sp. DOSMB-A107 isolated from mangrove sediments of Andaman Island, India

Authors: Baskaran, R.
Mohan, P. M.
Madanan, M.G.
Kumar, Ashok
Palaniswami, M.
Keywords: Andaman;Antimicrobial activity;Bioactive compounds;Streptomyces
Issue Date: May-2015
Publisher: NISCAIR-CSIR, India
Abstract:  In the present study, focused the antimicrobial compound production by the marine actinobacteria isolated from the mangrove sediments of Andaman Island. Streptomyces sp. DOSMB-A107 isolated from mangrove sediments of Andaman Island was identified by morphological, chemistry of cell wall and molecular characterization. Bioactive compounds were extracted with five different solvents and were identified using GC-MS analysis. Among the five different solvents ethyl acetate extract showed maximum activity against eleven bacteria and six fungal pathogens than other solvents. Twelve compounds were identified, off the following eight compounds such as 2-Butanol, 2-nitroso-, acetate(ester), Phenylethyl Alcohol, Phenol, 2,4-bis(1,1- dimethylethyl)-, 1-Hexadecanol, Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-3- (2-methylpropyl)-, 1Hentetracontanol, 1-Eicosanol, Ergotaman-3',6',18-trione, 12'-hydroxy-2'-methyl-5' (phenylmethyl)-, (5'à)- were identified as anti-infective agent. Ethyl acetate would be a suitable solvent for the extraction of antimicrobial agents from Streptomyces.
Page(s): 714-723
ISSN: 0975-1033 (Online); 0379-5136 (Print)
Appears in Collections:IJMS Vol.44(05) [May 2015]

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