NOPR Collection:

Ab initio and MNDO study of structural parameters and pyramidal phosphorus atom inversion in 1-substituted phosphorinanes

2016-07-20T05:23:44Z

Title: Ab initio and MNDO study of structural parameters and pyramidal phosphorus atom inversion in 1-substituted phosphorinanes Authors: Azizian, Javad; Jadidi, Khosrow; Mehrdad, Morteza; Sarrafi, Yaghob Abstract: A detailed ab initio and MNDO study of structural parameters and pyramidal phosphorus atom inversion and also enthalpy differences (∆H^o) between the participants in the conformational equilibrium... Page(s): 660-663

Glucopyranosyl derivatives of 4-aminoquinoline and 2-methylimidazo[1,2-α]-pyridine as potent reversible proton pump inhibitors^†

2016-07-20T05:28:13Z

Title: Glucopyranosyl derivatives of 4-aminoquinoline and 2-methylimidazo[1,2-α]-pyridine as potent reversible proton pump inhibitors^† Authors: Lohray, B B; Bhushan, Vidya; Reddy, A Sekar; Lakshminarayana, N; Rao, V Venugopal; Saibaba, V; Reddy, N Jaipal; Kumar, Prem; Reddy, K Narayan Abstract: Amongst a number of 4-aminoquinoline and 2-methylimidazo[1,2,-a]-pyridine derivatives examined 2-[3-butyryl-4-(2-methylphenylamino)quinoline-8-yloxy]ethyl 2,3,4,6-tetra-O-acetyl-β-D-glucopyranoside and 3-ethoxycarbonyl-2-methylimidazo[1,2-α]pyridine-8-yl 2,3,4,6-tetra-O-acetyl-β-D-glucopyranoside have been found to be good reversible proton pump inhibitors. Page(s): 635-638

Studies on the Himalayan yew Taxus wallichiana: Part VII - The taxoids and phenolic constituents of the roots of Taxus wallichiana^†

2016-07-20T05:36:52Z

Title: Studies on the Himalayan yew Taxus wallichiana: Part VII - The taxoids and phenolic constituents of the roots of Taxus wallichiana^† Authors: Chattopadhyay, S K; Kulshrestha, M; Tripathi, V; Saha, G C; Sharma, R P; Mehta, V K Abstract: The systematic investigation on the roots of Taxus wallichiana has resulted in the isolation of nine taxoids-taxol 1 baccatin III 2, baccatin IV 3, taxusin 4, a C-14 oxygenated taxoid 5, 1β-hydroxybaccatin I 6, pentaacetoxy taxadiene 7, a dibenzoylated rearranged taxoid 8, 7-xylosyl-10-deacetyl-taxol C 9 and three phenolic compounds (-) seco-isolariciresinol 11, taxiresinol 12 and isotaxiresinol 13. The compounds have been characterized on the basis of their spectral characteristics. The occurrence of taxoid 9 in the roots of the plant is quite significant. The distribution of the above compounds in other parts of the plant are also summarized. Page(s): 701-704

Synthesis and reactions of some new 5-aryl-3-oxo-7 -(4'-aryl-2' ,5 '-dioxo-1', 2' ,3 ', 4'-tetrahydrofluoren-3'-yl)-5H, 8H-2,3- dihydrothiazolo[5,4-b]pyrimidines of expected biological activity

2016-07-20T05:46:14Z

Title: Synthesis and reactions of some new 5-aryl-3-oxo-7 -(4'-aryl-2' ,5 '-dioxo-1', 2' ,3 ', 4'-tetrahydrofluoren-3'-yl)-5H, 8H-2,3- dihydrothiazolo[5,4-b]pyrimidines of expected biological activity Authors: Salama, M A; EI-Essa, S A Abstract: 2-Arylidene-indane-1,3-dione 1 on treatment with acetyl acetone in gl. acetic acid gives 3-acetyl-4-aryl-2,5-dioxo-1,2,3,4- tetrahydrofluorenes 2a-d which on reaction with benzaldehyde yield 4-aryl-3-cinnamoyl-2, 5-dioxo-1, 2, 3, 4-tetrahydrofluorenes 3a-d. Compounds 3a-d when reacted with thiourea in gl. CH₃COOH/Ac₂O in the presence of anhyd. sodium acetate afford 4,5-diaryl-6-(4'-aryl-2', 5' -dioxo-1', 2', 3', 4'-tetrahydrofluoren- 3'-yl)-1, 2, 3, 4-tetrahydropyrimidine-2-thiones 4a-d which on treatment with chloroacetic acid furnish 5-aryl-3-oxo-7-(4'-aryl- 2', 5' -dioxo-1',2',3',4' -tetrahydrofluoren-3'-yl)-5H, 8H-2,3-dihydrothi azolo[5,4-b]pyrimidines 5a-d. Compounds 5a-d on condensation with benzaldehyde yield 2-arylmethylene-3-oxo-Sphenyl-7-(4' -aryl-2', 5' -dioxo-1', 2', 3', 4'-tetrahydrotluoren-3'yl)-5H, 8H-2,3-dihydrothiazolo[5,4- b ]pyrimidines 6a-d. Page(s): 739-742

NOPR Collection:

Ab initio and MNDO study of structural parameters and pyramidal phosphorus atom inversion in 1-substituted phosphorinanes

Glucopyranosyl derivatives of 4-aminoquinoline and 2-methylimidazo[1,2-α]-pyridine as potent reversible proton pump inhibitors†

Studies on the Himalayan yew Taxus wallichiana: Part VII - The taxoids and phenolic constituents of the roots of Taxus wallichiana†

Synthesis and reactions of some new 5-aryl-3-oxo-7 -(4'-aryl-2' ,5 '-dioxo-1', 2' ,3 ', 4'-tetrahydrofluoren-3'-yl)-5H, 8H-2,3- dihydrothiazolo[5,4-b]pyrimidines of expected biological activity

Glucopyranosyl derivatives of 4-aminoquinoline and 2-methylimidazo[1,2-α]-pyridine as potent reversible proton pump inhibitors^†

Studies on the Himalayan yew Taxus wallichiana: Part VII - The taxoids and phenolic constituents of the roots of Taxus wallichiana^†