NOPR Collection:

Evaluation of anti-diarrhoeal activity of Quisqualis indica L. leaves

2013-08-01T16:34:37Z

Title: Evaluation of anti-diarrhoeal activity of Quisqualis indica L. leaves Authors: Singh, Nitu; Mohan, Govind; Sharma, Rajesh Kumar; Gnaneshwari, D Abstract: The aim of the present study is to evaluate the anti-diarrhoeal activity of the petroleum ether extract of leaves of Quisqualis indica L. against experimentally induced diarrhoea. Petroleum ether extract of the drug were evaluated for anti-diarrhoeal activity, using experimentally induced diarrhoea models: castor-oil induced diarrhoea, and charcoal induced gastrointestinal motility test in albino wistar rats of either sex. The earlier reported preliminary phytochemical screening of petroleum ether extracts revealed the presence of alkaloids, glycosides, flavonoids, tannins and phenolic compounds. petroleum ether extract of Quisqualis indica L. leaves at the doses (100, 200 mg/kg, p.o) were administered through the oral route. The plant extracts exhibited dose dependent anti-diarrhoeal effects in the all treated groups and the results were compared with that of standard drugs (Loperamide (3 mg/kg, p.o) and Atropine sulphate (0.1 mg/kg intraperitoneal), respectively as reference standard drugs. Statistically processed results support the conclusion, that the petroleum ether extracts of Quisqualis indica L. leaves (100 mg/kg and 200 mg/kg) possesses dose dependent, significant (P<0.05) antidiarrhoeal activity against experimentally induced diarrhoea. Page(s): 155-160

Evaluation of anti-inflammatory activity of Cynodon dactylon Pers. on carrageenan induced paw edema in rats

2013-07-25T16:33:53Z

Title: Evaluation of anti-inflammatory activity of Cynodon dactylon Pers. on carrageenan induced paw edema in rats Authors: Yogesh, H S; Kichadi, Shambhu C; Muchandi, I S; Gopalakrishna, B Abstract: In the present study, anti-inflammatory property of chloroform-methanolic extract isolated from Cynodon dactylon Pers. (Dhub Grass) was investigated in carrageenan induced rat paw edema. The extract showed significant inhibition of carrageenan induced paw edema at three doses of 125, 250 and 500 mg/kg used for both acute and chronic models in the study and is comparable with standard anti-inflammatory drug, Indomethacin. It can therefore be concluded from the present study that chloroform-methanolic extract of C. dactylon possesses anti-inflammatory property. Page(s): 151-154

Illicium griffithii Hook. f. & Thoms.-A potential source of natural off-farm income to the rural people of Arunachal Himalaya, India

2013-07-19T16:36:53Z

Title: Illicium griffithii Hook. f. & Thoms.-A potential source of natural off-farm income to the rural people of Arunachal Himalaya, India Authors: Paul, Ashish; Kalita, Janmoni; Khan, Mohamed Latif; Tripathi, Om Prakash Abstract: In the high altitude region of Arunachal Himalaya, hilly and undulating terrains have resulted into low agricultural crops production although majority of the local residents are highly dependent on the agriculture for their subsistence. Moreover, sources of income are scarce and peoples mainly depend on forest and forest products. Therefore, wild plant and animal species form an important component of livelihood of rural people in many parts. Illicium griffithii Hook.f. & Thoms. one of the significant aromatic and medicinal tree species occurring in subtropical to temperate forest of Arunachal Himalaya. However, the species is growing in selected forest patches to a few locations. Dried seed pods are economically valuable having good market potential for spices and pharmaceutical purposes. Fruit is considered to be carminative, aromatic stimulant, stomachic and galactagogue. It is used as medicine to cure abdominal pain, cough, dyspepsia, food poisoning, vomiting, toothache and sinusitis. It is also used as an antifungal agent and food preservative. Owing to its high demand, local inhabitants harvest large quantity of fruits every year. Collected seeds are sold in local market at the rate from 120 to 150/kg which mainly depends on the market demand. Fruits may also be a potential source of shikimic acid for the production of Tami flu (oseltamivir), an active drug against avian influenza or bird flu. Further investigations on its chemical aspects are required to meet the needs of shikimic acid for the country as well as global market. This is an important source of natural off-farm income to the rural people of the West Kameng district of Arunachal Pradesh where the present study was undertaken. Keeping economic values in consideration, I. griffithii has the tremendous potential to reduce the poverty and will also provide employment opportunity to the rural inhabitants through bio-prospecting of the species which will contribute towards the socio-economic development of the rural people of Arunachal Himalaya. Page(s): 131-137

Development and quality evaluation of beverages from Bottle Gourd, Lagenaria siceraria (Mol.) Standl.

2013-07-21T16:36:45Z

Title: Development and quality evaluation of beverages from Bottle Gourd, Lagenaria siceraria (Mol.) Standl. Authors: Vaidya, Devina; Rana, Neerja; Sharma, Surabhi; Mishra, Vigya Abstract: Cucurbitaceae family is a major source of medicinal agents since ancient times. Various plant parts including fruits of this family have been established for their pharmacological potential. Lagenaria siceraria (Mol.) Standl. (Family-Cucurbitaceae) commonly known as Lauki (Hindi) and Bottle gourd (English) is a medicinal plant. It is used as medicine in India, China, Euproean countries, Brazil, etc. for its cardiotonic, general tonic and diuretic properties. The vegetable has been widely used by the cardiac patients; this property may be correlated with the presence of radical scavenging activity. The juice of bottle gourd was determined for antioxidant activity by 1, 1-Diphenyl-2 picrylhydrazl (DPPH) assay and found high in the antioxidant activity (91%). However, vegetable juices are not consumed as such but this nutritive vegetable juice was utilized after blending with lemon juice and basil leaf extract to adjust the acidity and increase the palatability. After standardization of the ratio, this blend was used for the formulation of health nectars using honey as sweetener. Honey also being rich in nutrients and medicinal properties enhanced the health benefits of the nectar. Page(s): 219-222