NOPR Collection:

Selection of number of hidden neurons in neural networks in renewable energy systems

2016-07-20T04:55:42Z

Title: Selection of number of hidden neurons in neural networks in renewable energy systems Authors: Sheela, K G; Deepa, S N Abstract: This paper presents a new approach to select number of hidden neurons in neural network in renewable energy systems. The random selection of number of hidden neurons might cause over fitting and under fitting problems in neural networks. The proper selection of neurons in hidden layer is important in the design of neural network model. To fix hidden neurons, 91 various criteria are examined based on estimated mean squared error. The convergence analysis is performed for the various proposed criteria. To verify the effectiveness of the proposed model, simulations were conducted on real time wind data. Results show that with minimum error the proposed approach can be used in renewable energy systems. Page(s): 686-688

Enhancement of dissolution rate and bioavailability of Paliperidone by Hot Melt Extrusion technique

2016-07-20T04:55:00Z

Title: Enhancement of dissolution rate and bioavailability of Paliperidone by Hot Melt Extrusion technique Authors: Pandey, A; Rath, B; Dwivedi, A K Abstract: The purpose of the study was to increase the dissolution and bioavailability of BCS class II drug, paliperidone by amorphization. The technique that was evaluated for preparing amorphous paliperidone (PAL) was Hot Melt Extrusion (HME). In case of hot melt extrusion process, copovidone was used essentially as a hydrophilic polymer with plasticizers like PEG (6000 and 20000), stearic acid and cetosterayl alcohol. Melt extrusion process was carried out by using different concentrations of drug, polymer, and plasticizers. DSC studies showed that the crystalline nature of PAL was significantly reduced on melt extrude. Incorporation of the plasticizer resulted in faster drug release compared with extrudes without plasticizer. Out of the plasticizers studied extrudes prepared with 25% PEG 6000 showed rapid release, wherein more than 75% of drug release was achieved within 30 minutes. The pharmacokinetics of melt extruded composition (PAL with 25% PEG 6000) and pure PAL was evaluated following oral administration (0.8 mg/kg) in healthy female Sprague Dawley rats. The extent of the mean plasma exposures of PAL was 14-fold higher in animals treated with extruded mixture of PAL, compared to animals treated with PAL. Melt extruded of PAL with PEG, especially PEG 6000, reduced drug crystallinity, increased the rate and extent of dissolution, and improved bioavailability. Page(s): 680-685

Studies on the bioemulsifier production by a bacterial isolate

2016-07-20T04:53:59Z

Title: Studies on the bioemulsifier production by a bacterial isolate Authors: Kharangate-Lad, A; Bhosle, S Abstract: Bioemulsifiers have gained a lot of importance in biodegradation, bioremediation, medical, pharmaceutical and food industries due to their non-toxicity. In the present study bacteria producing bioemulsifier were isolated from mangroves and saltpans on mineral salt medium (MSS) containing crude oil as sole carbon source. Amongst the 19 isolates picked up to screen for bioemulsification activity, 9 isolates showed potential bioemulsification activities which were in the range of 2.0-45.5 % for pellets while 1.7-56.5% for supernatants. Two isolates MS-3 and MS-18 that showed the highest Emulsification index with supernatant were selected and identified based on biochemical characteristics as Aeromonas (MS-3) and Vibrio (MS-18) species. The isolate MS-3 was selected for detailed studies. The bioemulsifier was isolated, purified and characterised using TLC, FTIR and found to be glycolipid in nature. The critical micelle concentration (CMC) of the present emulsifier was found to be 12 mg/ ml with xylene as the hydrocarbon. Page(s): 674-679

Recovery and re-use of glass fibers for composite reinforcements

2016-07-20T04:52:24Z

Title: Recovery and re-use of glass fibers for composite reinforcements Authors: Adaganti, S Y Abstract: The fiber glass waste generated from composite Industries is difficult to dispose as they are hazardous to environment and are even found to be carcinogenic. Fiber glass recovered from the waste was collected and reused as reinforcement. Three boards of baggase with varied composition of glass fibers were prepared using urea formaldehyde resin as binder. The boards obtained were tested for strength and thermal property. The use of recovered glass fiber is extended to high strength cement applications wherein the glass fibers were reinforced with cement mortar and tested for compressive strength. The optimum percentage of glass fibers, to achieve maximum strength, in cement mortar was determined through this experiment. Page(s): 671-673