http://nopr.niscpr.res.in/handle/123456789/54 2026-10-06T05:22:37Z 2026-10-06T05:22:37Z Vishwakarma, Ram Majumdar, Pramila Jaggi, Monika http://nopr.niscpr.res.in/handle/123456789/68509 2026-09-21T09:15:25Z 2026-09-01T00:00:00Z

Title: EDITORIAL A new beginning Authors: Vishwakarma, Ram; Majumdar, Pramila; Jaggi, Monika Page(s): 367-368

2026-09-01T00:00:00Z Mattummal, Rubeena Kumar Koppala Narayana, Sunil Arumugam, Kanagarajan http://nopr.niscpr.res.in/handle/123456789/68458 2026-09-18T05:04:37Z 2026-09-01T00:00:00Z

Title: Systematic review on phytochemistry and ethnopharmacology of Brachypterum scandens (Roxb.) Wight & Arn.ex Miq. Authors: Mattummal, Rubeena; Kumar Koppala Narayana, Sunil; Arumugam, Kanagarajan Abstract: Brachypterum scandens (Roxb.) Wight & Arn.ex Miq. (syn. Derris scandens), an evergreen woody climber of the Fabaceae family, is widely recognised across Southeast Asia for its extensive application in traditional Indian, Chinese, and Thai medical systems. Ethnopharmacologically, the plant—particularly its stem, bark, and roots—is prescribed to alleviate musculoskeletal pain, osteoarthritis, inflammation, dysentery, and cardiovascular distress, and serves as an official herbal medicine in the Thai National List of Essential Medicines. Phytochemical investigations have revealed that B. scandens is rich in prenylated isoflavonoids, flavonoids, coumarins, triterpenoids, and phytosterols. Key bioactive compounds isolated include derrisisoflavones A–F, lupalbigenin, genistein-7-O-[α-rhamnopyranosyl-(1→6)-β-glucopyranoside] (GTG), 6,8- diprenylgenistein, scandenin, scandenone, betulinic acid, lupeol, and β-sitosterol. Pharmacological evaluations systematically validate these traditional claims, demonstrating potent anti-inflammatory effects through the inhibition of COX-2, iNOS, 5-LOX, TNF-α, and NF- NF-κB pathways. Furthermore, extracts and isolated phytoconstituents display significant cytotoxicity and pro-apoptotic activity against diverse human cancer cell lines (e.g., MCF-7, HT-29, HepG2, and A549), along with marked antimicrobial, antioxidant, wound-healing, hypoglycemic, thrombolytic, and insecticidal properties. This systematic review synthesises the ethnopharmacological applications, phytochemical profile, and reported pharmacological mechanisms of B. scandens, providing a scientific foundation for future targeted drug discovery and clinical development. Page(s): 369-380

2026-09-01T00:00:00Z Kumari, Mona N. Singh, Saurabh Gupta, Ena http://nopr.niscpr.res.in/handle/123456789/68457 2026-09-18T05:01:40Z 2026-09-01T00:00:00Z

Title: Pediococcus species: A lactic acid bacteria with promising therapeutic applications Authors: Kumari, Mona; N. Singh, Saurabh; Gupta, Ena Abstract: Pediococcus species, prominent Gram-positive lactic acid bacteria, exhibit significant biotechnological properties. A comprehensive literature search and review were conducted using several authentic electronic databases for the publication of recent studies to analyse relevant studies on Pediococcus species, antimicrobial metabolites, and their application in food preservatives that evidence the therapeutic efficacy of the species. The bacteriocin produced by these species provides antimicrobial activity that also enhances food quality by improving the flavour, texture, shelf-life, and nutritional quality of developed food products. Several researchers reported that among all species, P. acidilactici and P. pentosaceus are well-versed in enhancing functional and therapeutic properties. It produces antibacterial peptides, bacteriocins called pediocin, which are highly involved in food preservation. Additionally, P. acidilactici produces bioactive compounds that increase the levels of antioxidants, phenolics, flavonoids, and L-alanine to enhance nutritional quality. Pediococcus species possess probiotic properties as they can tolerate low gastric pH and bile salt, are non-hemolytic, and show antibacterial activities. P. acidilactici and P. pentosaceus demonstrateanti-proliferative and anticancer effects on cancer cells. P. parvulus also exhibits anti-inflammatory and anti-pathogenic properties, making it a suitable probiotic strain. P. damnosus demonstrated only a bacteriostatic effect on the pathogens; on the other hand, P. acidilactici and P. Pentosaceus show both bacteriostatic and bactericidal effects on pathogens. Additionally, some Pediococcus species are also involved in lowering glucose and cholesterol levels. However, Pediococcus species are generally regarded as safe (GRAS) and can be effectively utilised in the food industry. Various fermented foods, including dairy products, meat, fruits, and vegetables, and also in beer and wine making, are produced using Pediococcus as a starter culture. Pediococcus species are also efficient for the formulation of functional food asthey are potent for improving gut health and immune function. However, using Pediococcus species in food production is subject to regulation and safety considerations Page(s): 381-396

2026-09-01T00:00:00Z Jahan, Rownak Rahmatullah, Mohammed Mendonça, Diana Akter Mou, Farzana Nasir Ahmed, Md Akhter Khanam, Aseya Jannat, Khoshnur K. Paul, Tridib Alfi Afroze, Chowdhury Hany Rumi, Ommay Anwarul Bashar, A.B.M. V. Labana, Ryan K. Paul, Alok Wiart, Christophe de Lourdes Pereira, Maria Nissapatorn, Veeranoot http://nopr.niscpr.res.in/handle/123456789/68456 2026-09-18T04:59:09Z 2026-09-01T00:00:00Z

Title: Traditional plant-based remedies as supportive care for COVID-19 and diabetes in rural Bangladesh: A case study and exploratory review Authors: Jahan, Rownak; Rahmatullah, Mohammed; Mendonça, Diana; Akter Mou, Farzana; Nasir Ahmed, Md; Akhter Khanam, Aseya; Jannat, Khoshnur; K. Paul, Tridib; Alfi Afroze, Chowdhury; Hany Rumi, Ommay; Anwarul Bashar, A.B.M.; V. Labana, Ryan; K. Paul, Alok; Wiart, Christophe; de Lourdes Pereira, Maria; Nissapatorn, Veeranoot Abstract: COVID-19 has significantly impacted populations worldwide, particularly in resource-limited regions with limited access to conventional treatments. In some regions, traditional plant-based remedies are often used to reduce medication costs. However, their efficacy is usually not warranted. This study presents a case report of a woman from rural Bangladesh diagnosed with COVID-19 and with diabetes as a comorbidity. The patient used home remedies, including medicinal fruit intake and herbal steam inhalation, alongside conventional medications to manage her COVID-19 symptoms. No medication was taken for her diabetes due to costs. After a few months, the patient underwent another PCR test and was confirmed free of the virus. The potential alleviation of the patient's diabetes or blood sugar levels was coincidental due to the presence of antidiabetic phytochemicals in the remedies. An exploratory literature review examines the therapeutic potential of the phytochemicals present in the food and herbal medicines taken by the patient. The findings suggest that these plant-based interventions may support immune function and glycemic control, although further clinical studies are needed. This case highlights the importance of exploring culturally relevant, affordable, and accessible therapeutic options for managing COVID-19 and comorbidities in low-resource settings. Page(s): 397-411

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