http://nopr.niscpr.res.in/handle/123456789/65215 2026-10-10T17:27:28Z 2026-10-10T17:27:28Z Dutta, Sudev Bansal, Payal http://nopr.niscpr.res.in/handle/123456789/65229 2025-01-17T11:47:48Z 2025-01-01T00:00:00Z

Title: Hydrogel-based bio-inks: Current progress and future directions in 3D printing Authors: Dutta, Sudev; Bansal, Payal Abstract: Hydrogel-based bio-inks have become a cornerstone in the advancement of 3D bioprinting, particularly for tissue engineering applications. This review explores the current progress and future directions in the development of hydrogelbased bio-inks for 3D printing. Hydrogels, with their high water content and biocompatibility, closely mimic the natural extracellular matrix, making them highly suitable for creating tissue scaffolds. Recent advancements include the enhancement of mechanical properties, printability, and bioactivity through the incorporation of nanomaterials and the combination of natural and synthetic polymers. These improvements have led to better structural integrity and functional capabilities of printed scaffolds. The integration of bioactive molecules and growth factors within hydrogel matrices has further promoted cell proliferation and differentiation, and enhancing tissue regeneration. However, challenges such as the need for standardized protocols, improved printing resolution and precision, and the development of bio-inks that can support complex cellular microenvironments are still exiting. Future research is likely to focus on developing multifunctional bio-inks capable of adapting to diverse biological and mechanical needs. This includes stimuli-responsive hydrogels and novel bioprinting techniques like microfluidic-based and laser-assisted printing. Addressing these challenges and exploring new directions will significantly advance the field of tissue engineering and regenerative medicine. Page(s): 11-24

2025-01-01T00:00:00Z Kumar Bhonsle, Aman Trivedi, Jayati Porwal, Jyoti Rawat, Neha Agarwal, Tushar Singh, Jasvinder http://nopr.niscpr.res.in/handle/123456789/65228 2025-01-17T11:46:14Z 2025-01-01T00:00:00Z

Title: Effect of synthetic cold flow additives on properties of biodiesel and biodieseldiesel blends: A mini-review Authors: Kumar Bhonsle, Aman; Trivedi, Jayati; Porwal, Jyoti; Rawat, Neha; Agarwal, Tushar; Singh, Jasvinder Abstract: The demand for an alternative fuel to control fossil fuels is increasing, and biodiesel can play a crucial role in combatting the problems. Biodiesel that has been produced through various feedstocks employing different processes is a renewable and eco-friendly fuel. However, the generation of fewer emissions than fossil fuel makes it one favourable choice, but its marketability is still restricted due to poor cold flow behaviour and oxidation stability. In this review, we have focused on the cold flow problem of biodiesel which hampers functioning of diesel engines. This review particularly explores the types of synthetic additives, their mechanism of action, and their application in biodiesel-diesel blends in the last seven years. Page(s): 25-32

2025-01-01T00:00:00Z Raj, R. Shenbaga Madhu, P. Dhanalakshmi, C. Sowmya Prakash, M. Arul http://nopr.niscpr.res.in/handle/123456789/65227 2025-01-17T11:43:57Z 2025-01-01T00:00:00Z

Title: Application of CuO nanoparticles on performance and emission characteristics of ternary blends of diesel, waste cooking oil and pumpkin seed oil biodiesel in an IC engine Authors: Raj, R. Shenbaga; Madhu, P.; Dhanalakshmi, C. Sowmya; Prakash, M. Arul Abstract: The aim of this work is to demonstrate the effect of copper oxide (CuO) nanoparticles doped biodiesel on the performance and emission characteristics of a compression ignition (CI) engine. The base fuel (B20) is a ternary blend of 10% waste cooking oil (WCO) biodiesel, 10% pumpkin seed oil (PSO) biodiesel, and 80% conventional diesel. The B20 blend has been doped with CuO nanoparticles at four different dosage of 20, 40, 60 and 80 ppm. The tests are conducted on a single-cylinder diesel engine with no modifications and under standard operating conditions. WCO and PSO were identified for this work due to their good economic viability, and the oils are converted into biodiesel through the transesterification process. The performance parameters, such as brake thermal efficiency (BTE) and brake specific fuel consumption (BSFC) under different load conditions are evaluated. The emission characteristics of carbon monoxide (CO), hydrocarbons (HC), and oxides of nitrogen (NOx) are also considered for this study. From the results, it is found that the use of a ternary blend with CuO for an IC engine gives higher BTE with reduced BSFC. It is also perceived that the emission of CO and HC from the engine can be controlled with the addition of CuO nanoparticles. Page(s): 33-40

2025-01-01T00:00:00Z Pal, Srija Chatterjee, Niloy Chattopadhyay, Brajadulal Datta, Sriparna Dhar, Pubali http://nopr.niscpr.res.in/handle/123456789/65226 2025-01-17T11:41:54Z 2025-01-01T00:00:00Z

Title: Wealth from waste: Multifaceted yeast bio-synthesised sophorolipids using industrial waste by-products as substrate Authors: Pal, Srija; Chatterjee, Niloy; Chattopadhyay, Brajadulal; Datta, Sriparna; Dhar, Pubali Abstract: Sophorolipid biosurfactants are known for their versatile biological and physicochemical activities. This study explores its production, characterization, and biological activities utilising, palm fatty acid distillate (PFAD), a hydrophobic substrate derived from oil refinery waste by Starmerella bombicola, a native sophorolipid producing yeast. The sophorolipid yield is significantly enhanced by using PFAD than that of a vegetable oil used as feedstock. The yields are 36.71 and 18.62 g/L for PFAD and refined sunflower oil, respectively. The minimum surface tension with PFADSL (palm fatty acid distillate derived sophorolipid) is 37.73 mN/m and the CMC value is 76 mg/mL. Emulsifying properties of PFADSL are found to be 54.32%, 59.45%, and 28.38% for waste frying sesame oil, refined sesame oil, and petrol, respectively. The PFADSL is characterized using TLC, FTIR, and HPLC confirming the major component to be diacetylated lactonic sophorolipids (SLs) (C18:1) consisting 15.4% acidic forms ofsophorolipids. PFADSL showed minimum inhibitory concentration values ranging between 25 - 50 μg/mL against Proteus vulgaris, Shigella flexneri, Salmonella typhi, Vibrio cholerae, Staphylococcus aureus, Escherichia coli, Bacillus subtilis, and Klebsiella pneumoniae. Minimum Bactericidal Concentrations range from 300 to 500 μg/mL. SEM images show compromised membrane integrity against both gram-negative and positive bacteria. PFADSL also confirmed its strong biofilm inhibitory and eradication capacity against tested organisms. These findings reveal a noteworthy way of bio-converting oil industrial waste into a valuable product with potent surface lowering, emulsifying, antibacterial, and antibiofilm ability which can be a gem to various fields like biomedical, agricultural, pharmaceutical, cosmetics, nanotechnology, etc. Page(s): 41-56

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