NOPR Collection:

Isolation of two flavonol glycosides from the seeds of Acacia nilotica

2000-09-01T00:00:00Z

Title: Isolation of two flavonol glycosides from the seeds of Acacia nilotica Authors: Chauhan, Deepa; Singh, J; Siddiqui, I R Abstract: Two new flavonol glycosides viz. 5-hydroxy-7,4'-dimethoxy-8-isoprenylflavone-3-O-β-D-xylopyranoside and 5,7,3' ,4' -tetrahydroxy-6,8,2'-trimethoxyflavone-3-O-α-L-rhamnosyl (1→2)-O-β-D glucopyranoside have been isolated from the seeds of Acacianilotica (Linn). The structure of these glycosides have been established on the basis of chemical and spectral evidences. Page(s): 719-722

Kinetics of hydrolysis of 2-methyl/phenyl-3-(2'-hydroxybenzalamino)-quinazolin- 4(3H)-one

2000-09-01T00:00:00Z

Title: Kinetics of hydrolysis of 2-methyl/phenyl-3-(2'-hydroxybenzalamino)-quinazolin- 4(3H)-one Authors: Reddy, K Laxma; Upender, S; Reddy, K Adinarayana; Reddy, M Komal Abstract: Kinetics of hydrolysis of 2-methyl-3-(2'-hydroxybenzalamino) quinazolin-4(3H)-one (MHBQ) and 2-phenyl-3-(2'hydroxybenzalamino) quinazolin-4(3H)-one (PHBQ) have been studied. Rate coefficients have been measured for the alkaline hydrolysis of MHBQ and PHBQ in 70% (v/v) dioxane-water at various temperatures. The enthalpies and entropies of activation have been evaluated. The hydrolysis of MHBQ and PHBQ follows first order kinetics in both the substrate and the base. The relative rates of hydrolysis and activation parameters have been used to suggest the mechanism of the reactions. Page(s): 712-715

Formic acid with 10% palladium on carbon: A reagent for selective reduction of aromatic nitro compounds

2000-09-01T00:00:00Z

Title: Formic acid with 10% palladium on carbon: A reagent for selective reduction of aromatic nitro compounds Authors: Gowda, D Channe; Gowda, Shankare Abstract: The nitro group in aromatic nitro compounds also containing reducible substituents such as carbonyl, ethane,ethyne, nitrile, acid, phenol etc. is selectively and rapidly reduced at room temperature to corresponding amino derivatives in good yield employing formic acid in the presence of 10% palladium on carbon. The catalyst could be recovered and reused after washing with water and.ethanol, and the results obtained indicate further, there is no apparent loss of catalytic activity. Page(s): 709-711

A synthesis of some new 2-azetidinones as potential antitubercular agents

2000-09-01T00:00:00Z

Title: A synthesis of some new 2-azetidinones as potential antitubercular agents Authors: Parikh, Khyati A; Oza, Paresh S; Bhatt, S B; Parikh, A R Abstract: 2-Amino-4-(α-methoxyiminocarbmethoxymethyl) thiazole 1 on condensation with different aromatic aldehydes furnishes Schiff bases 2a-o which on treatment with chloroacetyl chloride in the presence of triethylamine as basic catalyst afford 2-azetidinones 3a-o. The synthesised compounds 3a-o have been tested in vitro for their antitubercular activity against Mycobacterium tuberculosis H37Rv. Page(s): 716-718