http://nopr.niscpr.res.in/handle/123456789/6002 2026-10-08T23:27:35Z http://nopr.niscpr.res.in/handle/123456789/30691 Title: <span style="mso-bidi-language:HI">Cytotoxic <i>ent-</i>kaurane<i> </i>diterpenoids from <i>Isodon racemosa </i>(Hemsl) Hara </span> Authors: Ding, Lan; Liu, Guo-An; Wang, Lai Abstract: <span style="mso-bidi-language:HI">A new <i>ent-kaurane </i>diterpenoid racemosin A <b>(1)</b> and three known compounds, leukamenin E <b>(2)</b>, glaucocalyxin A <b>(3)</b> and wangzaozin A <b>(4)</b>, have been isolated from the leaves of <i>Isodon racemosa </i>(Hemsl) Hara. The new diterpenoid is identified as 14β-hydroxy-3β, 7α-acetoxy-ent-kaur-16-en-15-one on the basis of spectral data, especially by 2D NMR techniques. Compounds <b>1-4</b> show significant cytotoxic activity against Bel-7402 and HO-89! 0 cells in the range of 1.51-2.57 and 3.33-4.02 µg/mL, respectively. This may be due to the presence of conjugated <i>exo</i>-methylene <span style="mso-bidi-language:HI">systen in an <i>ent-</i>kaurane<i> </i>skeleton. </span></span> Page(s): 548-551 2006-02-01T00:00:00Z http://nopr.niscpr.res.in/handle/123456789/30690 Title: Synthesis of pyrazolines, isoxazolines and aminopyrimidines as biological potent agents Authors: Solankee, Anjani; Thakor, Indrajit Abstract: <span style="mso-bidi-language:HI">Chalcones, 2-phenylamino-4-(4'-fluorophenylamino )-6-[4'-{3"-(phenyl/substituted phenyl/2"'- furanyl/3'"-pyridinyl)-2"- propenon-1<span style="mso-bidi-font-family: Arial;mso-bidi-language:HI">"-y1} <span style="mso-bidi-language: HI">phenylamino]-<i>s</i>-triazines <b>6a-j </b>have been prepared from ketone <b>5</b> based on <i>s</i>-triazine nucleus. These chalcones <b>6a-j</b> on cyclisation with hydrazine hydrate, hydroxylamine hydrochloride and guanidine nitrate give the corresponding pyrazolines <b>7a-j</b>, isoxazolines <b>8a-j</b> and <span style="mso-bidi-language:HI">aminopyrirnidines <b>9a-j</b>, respectively. Antimicrobial activities of all synthesized compounds have been performed by using cup-plate method against bacteria and by using poisoned food technique against fungi. The constitutions of newly synthesized <span style="mso-bidi-language:HI">compounds have been established on the basis of elemental analysis, IR and ^{<span style="mso-bidi-font-family:Arial; mso-bidi-language:HI">1</span>}<span style="mso-bidi-font-family:Arial; mso-bidi-language:HI">H <span style="mso-bidi-language:HI">NMR spectral data. </span></span></span></span></span></span></span> Page(s): 517-522 2006-02-01T00:00:00Z http://nopr.niscpr.res.in/handle/123456789/30689 Title: <span style="mso-bidi-language:HI">An efficient and chemoselective method for conversion of carbonyl compounds to 1,3-oxathiolanes with 2-mercaptoethanol catalyzed by TiCl_{<span style="mso-bidi-font-family:Arial;mso-bidi-language:HI">4</span>}<span style="mso-bidi-language:HI">-montmorillonitc </span></span> Authors: Jin, Tong-Shou; Zhao, Rui-Qiao; Ma, Yen-Ran; Yang, Mi-Na; Guo, Jun-Jic; Li, Tong-Shuang Abstract: <span style="mso-bidi-language:HI">Formation of 1,3-oxathiolanes from aldehydes and <span style="mso-bidi-font-family:Arial;mso-bidi-language:HI">ketones <span style="mso-bidi-language:HI">using 2-mercaptoethanol in the presence of TiCl_{<span style="mso-bidi-font-family:Arial;mso-bidi-language:HI">4</span>}<span style="mso-bidi-language:HI">-montmorillonite under mild reaction <span style="mso-bidi-font-family:Arial;mso-bidi-language:HI">conditions <span style="mso-bidi-language:HI">in <span style="mso-bidi-font-family:Arial; mso-bidi-language:HI">excellent <span style="mso-bidi-language:HI">yields is described. Chernoselective monothioacetalization of aldehyde in the <span style="font-size:12.0pt;font-family:" times="" new="" roman";mso-fareast-font-family:="" "times="" roman";mso-bidi-font-family:"times="" roman";mso-ansi-language:="" en-in;mso-fareast-language:en-in;mso-bidi-language:hi"="">presence of <span style="font-size:12.0pt;font-family:" times="" new="" roman";mso-fareast-font-family:="" "times="" roman";mso-bidi-font-family:arial;mso-ansi-language:en-in;="" mso-fareast-language:en-in;mso-bidi-language:hi"="">ketone <span style="font-size:12.0pt;font-family:" times="" new="" roman";mso-fareast-font-family:="" "times="" roman";mso-bidi-font-family:"times="" roman";mso-ansi-language:="" en-in;mso-fareast-language:en-in;mso-bidi-language:hi"="">can also <span style="font-size:12.0pt;font-family:" times="" new="" roman";mso-fareast-font-family:="" "times="" roman";mso-bidi-font-family:arial;mso-ansi-language:en-in;="" mso-fareast-language:en-in;mso-bidi-language:hi"="">he <span style="font-size:12.0pt;font-family:" times="" new="" roman";mso-fareast-font-family:="" "times="" roman";mso-bidi-font-family:"times="" roman";mso-ansi-language:="" en-in;mso-fareast-language:en-in;mso-bidi-language:hi"="">achieved in high yield. </span></span></span></span></span></span></span></span></span></span></span></span></span> Page(s): 503-505 2006-02-01T00:00:00Z http://nopr.niscpr.res.in/handle/123456789/6242 Title: Microwave assisted convenient and facile regeneration of carbonyl compounds from semicarbazones, phenylhydrazones and tosylhydrazones using phosphoric acid in solvent-free conditions Authors: Banerjee, Krishna; Mitra, Alok Kumar; Patra, Amarendra Abstract: Microwave irradiation of semicarbazones, phenylhydrazones and tosylhydrazones of carbonyl compounds with phosphoric acid under solvent-free conditions provides a fast, efficient and simple method for regeneration of carbonyls in excellent yields. Page(s): 537-539 2006-02-01T00:00:00Z