http://nopr.niscpr.res.in/handle/123456789/60714 2026-10-11T09:28:48Z http://nopr.niscpr.res.in/handle/123456789/60726 Title: Synthesis of glycoprotein inhibitory agents sinuxylamide A-E Authors: Annapurna, K; Rao, K Srinivasa; Narsaiah, A Venkat Abstract: Synthesis of naturally occurring Sinuxylamides A-E has been accomplished. Synthesis started from commercially available L-tyrosine. The key reactions involved in this synthesis are amide formation, Mitsunobu etherification and ester hydrolysis. Page(s): 1039-1045 2022-10-01T00:00:00Z http://nopr.niscpr.res.in/handle/123456789/60725 Title: Synthesis and antimicrobial activity of novel 5-methyl-1-(4-(6-methylimidazo [1,2-b]isoxazol-3-yl)phenyl)-3-aryl-1,3,5-triazinane-2-thiones Authors: Marri, Srinivas Abstract: Synthesis of novel 5-methyl-1-(4-(6-methylimidazo[1,2-b]isoxazol-3-yl)phenyl)-3-aryl-1,3,5-triazinane-2-thiones 6 has been achieved by the reaction of 3-amino-5-methylisoxazole 1 with p-nitrophenacyl bromide, followed by reduction of 3 with stannous chloride. Compounds 4 on treatment with different aryl isothiocyanates in refluxing benzene, followed by trimolecular condensation with 30% HCHO and methyl amine in ethanol affords the title compounds 6. The newly synthesized compounds 6 have been evaluated for their in vitro antimicrobial activity. Compounds 6 exhibit potent antimicrobial activity compared to that of standard drugs. Page(s): 1046-1053 2022-10-01T00:00:00Z http://nopr.niscpr.res.in/handle/123456789/60724 Title: Electrocoagulation for the efficient removal of Eriochrome Black T from wastewater using copper electrodes Authors: S, Mohan; P, Sharath; Nagabhushana, B M; Chikkahanumantharayappa; Shivakumara, C Abstract: The present study is based on the application of the electrocoagulation process in removal of Eriochrome Black T dye pollutant. It is found that many factors like voltage, temperature, number of pairs of electrodes, contact time, inter electrode distance are affecting the electrocoagulation. As voltage is increased from 5 V DC to 30 V DC the removal efficiency increases linearly and attained 98.3% at 13 V DC and beyond that the removal of dye is constant. The temperature plays important role in electrocoagulation and maximum removal was observed at 28 °C, at high temperature electrocoagulation decreases. It is also found that inter-electrode distance of 0.5 cm is more favourable for removal. As the number of pair of electrodes increases the removal capacity also increases. If there is a rise in concentration of the solution from 10 ppm to 1000 ppm the efficiency decreases from 99.2% to 63.6%. The chemical oxygen demand of the treated solution drops from 1600 to 320 ppm under 13 V DC, 180 s of contact time for 25 ppm of dye solution. The energy consumption, anode dissolution also plays a crucial role in removal of dye. Page(s): 1054-1064 2022-10-01T00:00:00Z http://nopr.niscpr.res.in/handle/123456789/60723 Title: Syntheses, spectral, thermal and pH-metric studies on bivalent metal ion complexes of N,N’-bis(3-carboxy-1-oxo-z-prop-2-elenyl)ethylenediamine Authors: Kumar, Vinod; Mittal, Sachin; Reddy, Malladi J.; Garg, Bhagwan S. Abstract: A novel carboxyamide ligand has been synthesized using maleic anhydride and ethylenediamine. Co(II), Ni(II), Cu(II) and Pd(II) complexes of the ligand, i.e., N,N’-bis(3-carboxy-1-oxo-z-prop-2-elenyl)ethylenediamine [H2L] have been prepared and characterized by elemental analyses, IR, electronic, 1H NMR, EPR spectral and thermal studies. It is revealed by IR and 1H NMR spectral studies that the ligand coordinated to the metal ions through deprotonated carboxylate oxygen and non-deprotonated amide nitrogen in all the complexes. It is suggested by electronic spectral and magnetic moment studies that N2O2 coordination is around each metal center with a strong field square planar chromophore. All the complexes have been studied by TGA and DTA studies done simultaneously. The complex formation between ligand and metal ions [Mn(II), Co(II), Ni(II), Cu(II) and Zn(II)] has also been studied pH metrically in 75% aqueous DMF solution at 298 K in 0.1 M NaClO4. The probable structures of the complexes have also been proposed. Page(s): 1065-1071 2022-10-01T00:00:00Z