http://nopr.niscpr.res.in/handle/123456789/66128 2026-10-12T08:40:57Z http://nopr.niscpr.res.in/handle/123456789/66148 Title: Biochemical and physicochemical characterization of traditional rice wine of Nyishi tribe of Arunachal Pradesh, India Authors: Kumari, Sony; Ama, Tarh; Jyoti Koch, Pranab; Debbarma, Rahel Abstract: Rice wine is a traditional alcoholic beverage of the Nyishi tribe of Arunachal Pradesh, prepared using 'Opo,' a traditional starter culture passed down through generations. This study investigates the biochemical significance of different rice wine varieties, focusing on their mineral content, bioactive components, and physicochemical properties. Mineral analysis revealed the presence of essential elements such as iron (Fe), calcium (Ca), zinc (Zn), and potassium (K). Among the studied varieties, Tisar wine exhibited the highest acceptability score, pH, alcohol content, and carbohydrate concentration, while Kecha wine was notable for its high protein, phenolic, and flavonoid contents. Bioactive compound analysis identified α-D-glucopyranoside in Adak wine and hexadecanoic acid in other varieties as the predominant components, contributing to the wines' potential health benefits. These findings provide valuable insights into the physicochemical and biochemical properties of traditional rice wine, highlighting its significance in indigenous practices and potential applications in functional foods. Page(s): 615-626 2025-07-01T00:00:00Z http://nopr.niscpr.res.in/handle/123456789/66147 Title: Compiling the wisdom of Kerala's indigenous farmers: A traditional rice pest management calendar Authors: K Sreejina, S; Nasser, M; K Nandakumar, M Abstract: This study documents traditional pest management practices among rice farmers in Kerala, emphasizing low-cost, ecologically grounded methods rooted in indigenous knowledge. Field surveys and interviews identified techniques including manual removal, sweeping with tools or aromatic plants, cultural practices (e.g., flooding, drainage), light traps, botanical and organic deterrents, cow dung slurry for seed treatment, and bioproducts like jeevamrutham and panchagavya. Vertebrate pests were managed using physical barriers, sound deterrents, and natural repellents. A seasonal pest management calendar was developed from these observations. The findings indicate that traditional practices can effectively reduce pest incidence and enhance plant health, though further scientific validation is needed for integration into formal Integrated Pest Management (IPM) frameworks. Page(s): 627-638 2025-07-01T00:00:00Z http://nopr.niscpr.res.in/handle/123456789/66146 Title: Deepana and Pachana activities of Pippali and Pippalimula (fruits and roots of Piper longum L.) and its effects on digestive enzymes of albino rats Authors: H Phadkea, Gayatri; Nariya, Mukeshkumar; Patel, Bhupesh Abstract: Pippali and Pippalimula are different parts of the plant Piper longum L. that belongs to the Piperaceae family. They have diversity in their Rasapanchaka (five attributes of drug) and hence may possess dissimilar pharmacological actions. This research study has been carried out to explore and compare the effects of these drugs on Deepana-Pachana activity, metabolic enzymes and hormones secreted in the gastrointestinal tract of albino rats. The effects of test drugs were assessed on food and water intake, food conversion ratio, gastric and intestinal enzymes and digestive hormones. Pippalimula showed significant results in body weight gain, water intake, as well as quantitative increase in amylase, lipase and trypsin levels in intestinal mucosa. While, Pippali demonstrated significant results in body weight gain and quantitative increase in Pepsin secretion in gastric mucosa of albino rats. Both the test drugs significantly increased food conversion ratio indicating improvement in digestion, metabolism, absorption and assimilation of food in albino rats. The findings underline that, Pippalimula has pronounced effects on intestinal digestive enzymes, while Pippali enhances the absorption and assimilation of food, indicating its Rasayana effect alongside Pippali’s Deepana action. These differences reflect the unique modes of action of the two parts of Piper longum L. based on inherent qualities, thus supporting the Ayurvedic perspective of drug-specific therapeutic applications. Page(s): 639-646 2025-07-01T00:00:00Z http://nopr.niscpr.res.in/handle/123456789/66145 Title: Efficacy of detoxifying and palliative Ayurvedic treatment on survival and quality of life in triple negative breast cancer patients Authors: Prabhakar Sardeshmukh, Sadanand; Vishnu Kulkarni, Arvind; Vishvasrao Patil, Tushar; Vasant Deshmukh, Vineeta; Rajesh Godse, Vasanti; Mahadeo Datar, Shrinivas; Jaideep Kulkarni, Swapna; Narayan Gore, Sameer; Rakesh Gujar, Shweta; Yogesh Shingte, Anita; Anaji Radye, Vijay; Sumeet Shivgankar, Sushama; Tushar Dalvi, Sneha; Sukumar Sardeshmukh, Bhagyashree; Sushrut Sardeshmukh, Nilambari; Ravindra Deshpande, Dhananjay; Sanjog Awalkanthe, Vinita; Aniruddha Deshpande, Anajli; Sumant Salunkhe, Abhishek; Abhishek Salunkhe, Amruta; Kishor Shiraskar, Suchita; Bhagwan Chavan, Sandeep Abstract: Triple Negative Breast Cancer (TNBC) accounts for ~10-20% of invasive breast cancers and has an early recurrence and aggressive metastases. It is a heterogeneous disease based on immunohistochemistry as estrogen, progesterone, and human epidermal growth factor-2 receptors are negative. Thus, hormonal treatment is not offered to TNBC patients after completion of conventional treatment like other types of breast cancer patients. In this scenario, alternative medicines like Ayurveda are the day‘s need. According to Ayurveda, vitiated Vata, Pitta, and Kapha impair Jatharagni (digestive power) and Dhatvagni (digestive power of each tissue), disrupting dhatu metabolism (Rasa to Meda). This forms deep, firm, slow-growing, non-suppurative tumors at impaired sites like the breast, with progressive dhatu (deeper tissue) involvement (Dhatugatavastha), which is known as Dushta Stana Granthi (malignant breast nodes) or Arbuda (malignant breast tumour). In such a situation, Ayurveda describes Shamana (Dosha pacification), Rasayana (Rejuvenation), and Shodhana i.e., Panchakarma (body detoxification) as the main treatment modalities. Oral Ayurvedic medicines (OAM) consisting of Shamana and Rasayana are known to improve quality of life and immunity boosting in many diseases including cancer whereas Panchakarma (PNK) detoxifies body and thus helps to minimize the risk of recurrence. The main aim of this study was to study the efficacy of Ayurvedic treatment as well as comparing effect of treatment modalities viz., Shamana with Rasayana (SR) and Shamana with Rasayana and Panchakarma (SRP) on survival and Quality of life (QoL) in TNBC patients. In this retrospective study, 68 patients diagnosed with TNBC, irrespective of stage and grade, with ongoing or completed conventional treatment and taken Ayurvedic treatment for more than 6 months were included. QoL was studied by using standard questionnaires while Disease-free Survival (DFS) and Overall survival (OS) were assessed by radiological and biochemical parameters. DFS was found in maximum patients (75%) and progression in only 25% of patients also highlight the efficacy of Ayurvedic treatment to control the disease. Longer DFS and OS were seen in the patients treated with SRP as compared to SR. Significant improvement in functional, symptom, global, and Karnofsky performance scores of all patients indicated improved QoL and well-being after Ayurvedic treatment. These results are indicative of efficacy of Ayurvedic treatment to increase survival and improve QoL of TNBC patients. Especially, SRP treatments are more beneficial to increase DFS and OS thus emphasizing the necessity of detoxifying PNK treatment in addition to OAM in TNBC patients. Page(s): 647-656 2025-07-01T00:00:00Z