NOPR Collection:

Facile PTSH-catalysed Beckmann rearrangement of ketoximes in solid state

Thu, 01 Jul 1999 00:00:00 GMT

Title: Facile PTSH-catalysed Beckmann rearrangement of ketoximes in solid state Authors: Ponnusamy, S; Pitchumani, K Abstract: Beckmann rearrangement of acetone oxime, acetophenone oxime and benzophenone oxime has been studied in the presence of para-toluenesulphonic acid as a solid catalyst. The rearrangement is found to proceed smoothly and under milder conditions. It is observed that in the case of benzophenone oxime, elevated temperatures favour rearrangement, while deoximation is predominant at room temperature. An explanation is presented and the mechanism is discussed. Page(s): 861-864

Synthesis of some 4-aryl- 1, 2, 3, 4- tetrahydrobenzopyrano [4, 3-d] pyrimidine- 2,5-diones/pyrimidine-2-thioxo-5–ones

Thu, 01 Jul 1999 00:00:00 GMT

Title: Synthesis of some 4-aryl- 1, 2, 3, 4- tetrahydrobenzopyrano [4, 3-d] pyrimidine- 2,5-diones/pyrimidine-2-thioxo-5–ones Authors: Brahmbhatt, D I; Raolji, Gajendra B; Pandya, Shashi U; Pandya, Urvish R Abstract: Various 4-aryl-1, 2, 3, 4-tetrahydro-benzopyrano[4, 3-d] pyrimidine- 2, 5-diones 3a-1 and 4-aryl-1, 2, 3, 4-tetrahydrobenzopyrano [4, 3-d] pyrimidine-2-thioxo-5-ones 3m-x have been synthesised by reacting 4-hydroxycoumarins 1a-c with aromatic aldehydes 2a-d in the presence of urea/thiourea under Biginelli reaction conditions. Page(s): 839-842

The investigation of nucleophilic reactions of 3-bromo/chloro phthalide with amines

Thu, 01 Jul 1999 00:00:00 GMT

Title: The investigation of nucleophilic reactions of 3-bromo/chloro phthalide with amines Authors: Desai, R A; Chaphekar, S S; Samant, S D Abstract: The reaction of 3-bromo/chloro phthalide 1a/b with secondary amines in polar solvents gives the corresponding amides of 2-formylbenzoic acid, while in nonpolar solvents gives 3-aminophthalides. The reaction of 1a/b with aromatic primary amines gives 3-arylaminophthalides, while with aliphatic primary amines 3-hydroxyphthalimidines are obtained. Page(s): 810-813

Synthesis of an analogue of the naturally occuring Aristotelia indole alkaloid, fruticosoline

Thu, 01 Jul 1999 00:00:00 GMT

Title: Synthesis of an analogue of the naturally occuring Aristotelia indole alkaloid, fruticosoline Authors: Hashem, Md. Abul; Sultana, Israt; Hai, Md. Abdul Abstract: A synthesis of an analogue of the rare Aristotelia indole alkaloids is reported. The monoterpene, Pulegone, 1 on nitromethylation give nitromethylpulegone, 2, which on reduction with LiAlH₄ and as well as with NaBH₄ yield the compounds 3, 4 and 5. The amino-alcohol 5 is condensed with indolyloxalyl chloride 6 to furnish the -ketoamide 7, which is converted to the corresponding monoterpenoid indole alkaloid 8, an analogue of fruticosoline 9. Page(s): 789-794