http://nopr.niscpr.res.in/handle/123456789/1722 Mon, 05 Oct 2026 11:53:55 GMT 2026-10-05T11:53:55Z http://nopr.niscpr.res.in/handle/123456789/1752 Title: Ceric(IV) ammonium nitrate catalyzed synthesis of β-enaminones Authors: Paira, M; Misra, R; Roy, S C Abstract: β-Enaminones have been synthesized in good yield from 1,3-dicarbonyl compounds and activated amines in the presence of ceric ammonium nitrate as catalyst. Page(s): 966-969 Sun, 01 Jun 2008 00:00:00 GMT http://nopr.niscpr.res.in/handle/123456789/1752 2008-06-01T00:00:00Z http://nopr.niscpr.res.in/handle/123456789/1751 Title: Beckmann rearrangement of α-oximinoketones Authors: Kumar, B N Hitesh; Prakasam, T; Srinivasan, P S; Arabindoo, Bhanumathi; Ramana, D V Abstract: The Beckmann rearrangement of α-oximinoketones gives benzoic acids as chief isolable products. Both first order and second order Beckmann rearrangements have been observed. The occurrence of first order Beckmann rearrangement in these oximinocarbonyl compounds is confirmed through the identification of the products obtained. Page(s): 963-965 Sun, 01 Jun 2008 00:00:00 GMT http://nopr.niscpr.res.in/handle/123456789/1751 2008-06-01T00:00:00Z http://nopr.niscpr.res.in/handle/123456789/1750 Title: Quantitative structure-activity relationship studies of a new class of selective aldose reductase inhibitors Authors: Sharma, R; Sahoo, P K; Chaturvedi, S C Abstract: Quantitative structure activity relationship studies on a series of [1,2,4]Triazino[4,3-a] benzimidazole acetic acid derivatives with selective aldose reductase inhibitor activity is made using a combination of various physicochemical descriptors. This is a new class of triazino benzimidazole derivatives having selective activity with minimum toxic effects. Several significant equations with good co-efficient of correlation (≥ 0.854) are obtained; the best model is selected using predictive ability of equations. The model shows positive contribution of logP towards biological activity i.e., high hydrophobic nature of the molecules might be increasing the selective aldose reductase inhibitor activity. Page(s): 957-962 Sun, 01 Jun 2008 00:00:00 GMT http://nopr.niscpr.res.in/handle/123456789/1750 2008-06-01T00:00:00Z http://nopr.niscpr.res.in/handle/123456789/1748 Title: Chemical constituents of Dendrobium gratiosissimum and their cytotoxic activities Authors: Zhang, Chao-Feng; Wang, Min; Wang, Lei; Iinuma, Munekazu; Zhang, Mian; Xu, Luo-Shan; Wang, Zheng-Tao Abstract: Two new bibenzyl derivatives, named dengraols A 1 and B 2, are isolated from stems of Dendrobium gratiosissimum Rchb. (Orchidaceae), together with seven known compounds: 3,5,4′-trihydroxybibenzyl 3, 3,4′-dihydroxy- 5-methoxybibenzyl 4, 3, 4 - dihydroxy-5, 4′ - dimethoxy bibenzyl 5, 3, 4′ - dihydroxy - 4, 5, 3′-trimethoxybibenzyl (moscatilin) 6 and 5, 4′- dihydroxy -3, 3′- dimethoxybibenzyl (gigantol) 7, 5, 3′, 4′-trihydroxy - 3- methoxybibenzyl (tristin) 8 and 5, 3′- dihydroxy- 3-methoxybibenzyl (batatasin III) 9. Among the isolated compounds, dengraols A 1 and B 2, moscatilin 6 and gigantol 7 showed inhibitory activity of proliferation on HL-60 cells with IC₅₀ values at 2.1, 6.4, 0.082 and 10.6 μM, respectively. Page(s): 952-956 Sun, 01 Jun 2008 00:00:00 GMT http://nopr.niscpr.res.in/handle/123456789/1748 2008-06-01T00:00:00Z