NOPR Collection: http://nopr.niscpr.res.in/handle/123456789/61370 Fri, 09 Oct 2026 20:31:01 GMT 2026-10-09T20:31:01Z Synthesis, characterization, antimicrobial and antitubercular activity of some new pyrimidine derivatives http://nopr.niscpr.res.in/handle/123456789/61382 Title: Synthesis, characterization, antimicrobial and antitubercular activity of some new pyrimidine derivatives Authors: Desai, Siddharth; Sastry, Girija; Singh Chatrapati, Kishore Abstract: Pyrimidine heterocycles are proven to be biologically active heterocycles, found in many biological systems, displaying a broad spectrum of biological activities including anticancer, anxiolytic, antioxidant, antiviral, antifungal, anticonvulsant, antidepressant and antibacterial activities. New substituted 2-oxopyrimidines have been synthesized from the chalcones linked via indane-1,3-dione moity by the methods discussed in experimental section. We have synthesized some new 2-[6- (substituted phenyl)-2-oxo-1,2,5,6-tetrahydropyrimidin-4-yl]-indane-1,3-dione by reacting chalcones (step-1 compounds have been reported by us) with urea. Page(s): 11-15 Sun, 01 Jan 2023 00:00:00 GMT http://nopr.niscpr.res.in/handle/123456789/61382 2023-01-01T00:00:00Z Fe3O4 supported acidic ionic liquid: An efficient and recyclable magnetic nanoparticles catalyst for one-pot synthesis of Bis(indolyl)methanes http://nopr.niscpr.res.in/handle/123456789/61381 Title: Fe3O4 supported acidic ionic liquid: An efficient and recyclable magnetic nanoparticles catalyst for one-pot synthesis of Bis(indolyl)methanes Authors: Rani, Jims World Star; Sing Nongthombam, Geetmani; Kathing, Chingrishon; Nongrum, Ridaphun; Kupar Kharmawlong, George; Nongkhlaw, Rishanlang Abstract: Bis(indolyl)methane derivatives are efficiently synthesized from indole/2-methyl indole and aldehydes using acidic ionic liquid immobilized on magnetic Fe3O4 nanoparticles. Catalyst used in this methodology is synthesized and characterized using various techniques like FT-IR, TGA, TEM, EDX, Powdered XRD and VSM. The catalyst can be easily retrieved by an external magnet and has been reused up to five runs without any appreciable loss of its catalytic activity. Page(s): 16-23 Sun, 01 Jan 2023 00:00:00 GMT http://nopr.niscpr.res.in/handle/123456789/61381 2023-01-01T00:00:00Z Feasible pathways for the multi-dimensional synthesis of carboxylic acid from benzo-pyrone methyl ketone http://nopr.niscpr.res.in/handle/123456789/61380 Title: Feasible pathways for the multi-dimensional synthesis of carboxylic acid from benzo-pyrone methyl ketone Authors: Yarva, Aruna; Nagamalla, Lavanya; K, Kavitha; Pasula, Aparna; Devulapally, Srikrishna; Kumar Dubey, Pramod Abstract: 3-Acetyl coumarin derivatives are the key synthons to the numerous numbers of heterocyclic compound syntheses.Due to the wide spectrum applications of benzopyran derivatives in pharma, research, food technology and material science there is a multitude number of methodologies feasible to synthesize benzo pyrone heterocyclic derivatives. This article articulates the synthesis and molecular structure confirmation of oxidative product starting from methyl ketone compound by haloform reaction. Design of benign path ways for instance room temperature, reflux conditions and water bath mediated synthesis of desired compounds in expected yields is the foremost intent of the article. Solvent and catalyst optimization studies were carried to elevate the product yield and to precede the reaction in sustainable way. Furthermore compounds are confirmed by spectroscopic analytical methods such as 1H NMR, 13C NMR, IR and HRMS spectroscopy. This article paves the way to researchers to explore these analogues to explore disparate medicinal applications. Page(s): 24-30 Sun, 01 Jan 2023 00:00:00 GMT http://nopr.niscpr.res.in/handle/123456789/61380 2023-01-01T00:00:00Z Electro-catalyzed cynoarylmethylation of isatin for synthesis of 3-hydroxy-3-cynomethyl oxindole derivatives http://nopr.niscpr.res.in/handle/123456789/61379 Title: Electro-catalyzed cynoarylmethylation of isatin for synthesis of 3-hydroxy-3-cynomethyl oxindole derivatives Authors: Kumar Singh, Vinay; Upadhyay, Abhishek; Dubey, Rahul; Prakash, Ved; Kumar Patel, Manoj; Sharma, Laxmi Kant; Pal Singh, Rana Krishna Abstract: An efficient and economical method has been developed for synthesis of 3-substituted oxindole by using electrochemically induced condensation of various N-substituted isatin, phenyl acetonitrile. Page(s): 31-37 Sun, 01 Jan 2023 00:00:00 GMT http://nopr.niscpr.res.in/handle/123456789/61379 2023-01-01T00:00:00Z