NOPR Collection:

Synthesis and biological activities of new 7-o--D-glucopyranosyloxy-3-(3-oxo-3-arylprop-1-enyl)-chromones

Sun, 01 Nov 2009 00:00:00 GMT

Title: Synthesis and biological activities of new 7-o--D-glucopyranosyloxy-3-(3-oxo-3-arylprop-1-enyl)-chromones Authors: Hatzade, K M; Taile, V S; Gaidhane, P K; Umare, V D; Haldar, A G M; Ingle, V N Abstract: A convenient route to synthesize some new medicinally important 7-hydroxy-3-(3-oxo-3-arylprop-1-enyl)-chromones 2 is described by the interaction of 7-hydroxy-3-formyl chromone 1 with various substituted acetophenones which on condensation with 2,3,4,6-tetra-o-acetyl--D-glucopyranosyl bromide affords 2,3,4,6-tetra-o-acetyl--D-glucopyranosyloxy-3-(3-oxo-3-arylprop-1-enyl)-4H-chromen-4-ones 3. Later on deacetylation with anhydrous zinc acetate in methanol gives 7-o--D-glucopyranosyloxy-3-(3-oxo-3-arylprop-1-enyl)-4H-chromen-4-ones 4. These compounds are evaluated for their in vitro antimicrobial and antioxidant activity. The structures of these newly synthesized compounds are established by IR, NMR, mass spectra, elemental analysis and chemical analysis. Page(s): 1548-1557

Novel fluorescence emissions from 3-styrylindoles

Sun, 01 Nov 2009 00:00:00 GMT

Title: Novel fluorescence emissions from 3-styrylindoles Authors: Singh, Anil K; Asefa, Abera Abstract: Fluorescence spectral properties of variously substituted 3-styrylindoles viz. 3-(2-phenylethenyl-E)-NH-indole 1, 3-[2-(4-nitrophenyl)ethenyl-E]-NH-indole 2, 5-methoxy-3-[2-(4-nitrophenyl)ethenyl-E]-NH-indole 3,3-[2-(4-chlorophenyl)ethenyl-E]-NH-indole 4 and 5-methoxy-3-[2-(4-chlorophenyl)ethenyl-E]-NH-indole 5 in solution and solid-state are described. Page(s): 1543-1547

Synthesis of quinoxaline quinones and regioselectivity in their Diels-Alder cycloadditions

Sun, 01 Nov 2009 00:00:00 GMT

Title: Synthesis of quinoxaline quinones and regioselectivity in their Diels-Alder cycloadditions Authors: Sharma, Gitanjali; Raisinghani, Pankaj; Abraham, Ignatious; Pardasani, R T; Mukherjee, Tulsi Abstract: A facile synthesis of quinoxaline quinones is reported. The regioselectivity in their Diels-Alder cycloaddition reactions has been investigated at AM1 level using Gaussian 98 and MOPAC 6 programs. The products have been characterized from their spectral data. Page(s): 1590-1596

Microwave assisted synthesis and antimicrobial activity of some 2-(benzo- furan-2-yl) -7-(substituted)imidazo[2,1-b]benzothiazoles

Sun, 01 Nov 2009 00:00:00 GMT

Title: Microwave assisted synthesis and antimicrobial activity of some 2-(benzo- furan-2-yl) -7-(substituted)imidazo[2,1-b]benzothiazoles Authors: Rani, Rekha; Makrandi, J K Abstract: 2-(Benzofuran-2-yl)-7-(substituted)imidazo[2,1-b]benzothiazoles have been prepared by condensation of 2-(2-bromoacetyl)benzofurans and various 2-amino-7-(substituted) benzothiazoles under normal thermal condition as well as microwave irradiations. The latter condition for the reaction has been found to be much more efficient in terms of time and yield. The structures of the compounds have been established on the basis of their elemental analysis, IR and ¹H NMR spectral data. The antibacterial and antifungal properties of these compounds are described. Page(s): 1614-1617

NOPR Collection:

Synthesis and biological activities of new 7-o--D-glucopyranosyloxy-3-(3-oxo-3-arylprop-1-enyl)-chromones

Novel fluorescence emissions from 3-styrylindoles

Synthesis of quinoxaline quinones and regioselectivity in their Diels-Alder cycloadditions

Microwave assisted synthesis and antimicrobial activity of some 2-(benzo­- furan-2-yl) -7-(substituted)imidazo[2,1-b]benzothiazoles

Microwave assisted synthesis and antimicrobial activity of some 2-(benzo- furan-2-yl) -7-(substituted)imidazo[2,1-b]benzothiazoles