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http://nopr.niscpr.res.in/handle/123456789/10022| Title: | Antifouling sesquiterpene from the Indian soft coral, Sinularia kavarattiensis Alderslade and Prita |
| Authors: | Mol, V P Limna Raveendran, T V Parameswaran, P S Kunnath, R J Sathyan, N |
| Keywords: | Soft coral;Sinularia kavarattiensis;Sesquiterpene;Furoic acid; Balanus amphitrite |
| Issue Date: | Jun-2010 |
| Publisher: | CSIR |
| Abstract: | A sesquiterpene, (l'E,5'E)-2-(2',6'-dimethylocta-l',5',7'-trienyl)-4-furoic acid [1], was isolated for the first time from the soft coral Sinularia kavarattiensis Alderslade & Prita collected from Gulf of Mannar (Tamil Nadu, India). This compound exhibited considerable larval settlement inhibition properties against the cosmopolitan biofouler, Balanus amphitrite. The observed mean EC50 value of 11.21 µg/ml is well within the biological potency cut off set for natural product antifoulants (NPA’s). The low EC50 value and favourable therapeutic ratio (5.16) coupled with its known synthetic routes enhances the potential of 1 as a promising NPA. |
| Page(s): | 270-273 |
| ISSN: | 0975-1033 (Online); 0379-5136 (Print) |
| Appears in Collections: | IJMS Vol.39(2) [June 2010] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJMS 39(2) 270-273.pdf | 99 kB | Adobe PDF | View/Open |
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