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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Banerjee, Subham | - |
| dc.contributor.author | Chaurasia, Gaurav | - |
| dc.contributor.author | Pal, Dilipkumar | - |
| dc.contributor.author | Ghosh, Ashoke Kumar | - |
| dc.contributor.author | Ghosh, Animesh | - |
| dc.contributor.author | Kaity, Santanu | - |
| dc.date.accessioned | 2010-09-30T10:07:32Z | - |
| dc.date.available | 2010-09-30T10:07:32Z | - |
| dc.date.issued | 2010-10 | - |
| dc.identifier.issn | 0975-1084 (Online); 0022-4456 (Print) | - |
| dc.identifier.uri | http://hdl.handle.net/123456789/10302 | - |
| dc.description | 777-784 | en_US |
| dc.description.abstract | Interpenetrating polymer
network (IPN) based formulation, consisting of sodium alginate and poly vinyl
alcohol,
were prepared by water-in-oil
emulsion crosslinking method. IPN based formulation was cross-linked with
glutaraldehyde, and
loaded with diclofenac sodium
(DS) as a model drug. Scanning electron microscopy revealed spherical nature of
microspheres
(size, 472-157  m). Drug entrapment efficiency
(72%) was obtained depending upon concentration of crosslinking density.
Novel formulation can be a potential carrier for controlled delivery of
short half-lived drugs. | en_US |
| dc.language.iso | en_US | en_US |
| dc.publisher | NISCAIR-CSIR, India | en_US |
| dc.rights |  CC Attribution-Noncommercial-No Derivative Works 2.5 India | en_US |
| dc.source | JSIR Vol.69(10) [October 2010] | en_US |
| dc.subject | Controlled release | en_US |
| dc.subject | Crosslinking agent | en_US |
| dc.subject | Interpenetrating polymer network | en_US |
| dc.subject | Microspheres | en_US |
| dc.title | Investigation on crosslinking density for development of novel interpenetrating polymer network (IPN) based formulation | en_US |
| dc.type | Article | en_US |
| Appears in Collections: | JSIR Vol.69(10) [October 2010] | |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| JSIR 69(10) 777-784.pdf | 332.37 kB | Adobe PDF | View/Open |
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