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http://nopr.niscpr.res.in/handle/123456789/10501| Title: | Performance of CFC free propellant- driven MDI of fluticasone propionate |
| Authors: | Murthy, T E G K Priya, M Bala Vishnu Satyanarayana, V |
| Keywords: | Emitted dose;Fluticasone propionate;Metered dose inhalers;Overages;Spray pattern;Valve delivery |
| Issue Date: | Nov-2010 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | Metered dose inhalers (MDIs) of fluticasone propionate were developed for treatment of asthma and chronic obstructive pulmonary disease. MDIs with hydrofluoroalkanes based propellants were formulated with various doses, overages and various concentrations of alcohol. Optimum requirements were found as follows: effective valve delivery, overdoses (15%); 100% drug delivery, overages (20%); and emitted dose and fine particle fraction, alcohol content (5-10%). |
| Page(s): | 866-871 |
| ISSN: | 0975-1084 (Online); 0022-4456 (Print) |
| Appears in Collections: | JSIR Vol.69(11) [November 2010] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| JSIR 69(11) 866-871.pdf | 275.28 kB | Adobe PDF | View/Open |
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