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http://nopr.niscpr.res.in/handle/123456789/11230| Title: | Bacterial model systems for cytochrome c oxidase biogenesis |
| Authors: | Hannappel, A Bundschuh, F A Greiner, P Alles, M Werner, C Richter, O M Ludwig, B |
| Keywords: | Bioinorganic chemistry;Biogenesis;Oxidase assembly;Terminal oxidase;Heme copper oxidase;Chaperone proteins;Heme a;Surf1;CbaX;CtaG;Cox11;Sco |
| Issue Date: | Mar-2011 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | Cytochrome c oxidase is the key player in cellular respiration, catalysing the reduction of molecular oxygen to water via its internal heme and copper redox centres. Biogenesis of the enzyme is a complex process involving up to 30 accessory proteins in higher eukaryotes. Factors directly involved in cofactor recruitment and insertion into the two core structural subunits I and II are also present in many bacteria and have been conserved during evolution. Herein we briefly review the chaperones required during early biogenesis steps, with special emphasis on the bacterial counterparts. |
| Page(s): | 374-382 |
| ISSN: | 0975-0975(Online); 0376-4710(Print) |
| Appears in Collections: | IJC-A Vol.50A(03-04) [March-April 2011] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCA 50A(03-04) 374-382.pdf | 261.83 kB | Adobe PDF | View/Open |
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