Please use this identifier to cite or link to this item: http://nopr.niscpr.res.in/handle/123456789/12615
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dc.contributor.authorChandra, Amar K-
dc.contributor.authorChoudhury, Shyamosree Roy-
dc.contributor.authorDe, Neela-
dc.contributor.authorSarkar, Mahitosh-
dc.date.accessioned2011-08-29T06:43:45Z-
dc.date.available2011-08-29T06:43:45Z-
dc.date.issued2011-09-
dc.identifier.issn0975-1009 (Online); 0019-5189 (Print)-
dc.identifier.urihttp://hdl.handle.net/123456789/12615-
dc.description689-697en_US
dc.description.abstractGreen tea, prepared from the steamed and dried leaves of the shrub Camellia sinensis, is known for its antioxidant and anti-carcinogenic effects. However, its effects on male gonadal functions have not been explored adequately and the present investigation has been undertaken to evaluate the effect of green tea extract on gonads of adult male albino rats. Results of in vivo studies showed that green tea extract (GTE) at mild (1.25 g%, ≡ 5 cups of tea/day), moderate (2.5 g%, ≡ 10 cups of tea/day) and high (5.0 g%, ≡ 20 cups of tea/day) doses, for a period of 26 days, altered morphology and histology of testis and accessory sex organs. A significant dose-dependent decrease in the sperm counts, inhibited activities of testicular ∆53- and 17-hydroxysteroid dehydrogenase (∆5-3-HSD and 17-HSD respectively) and decreased serum testosterone level were noticed. Significant increase in serum LH level was observed after moderate and high doses; serum FSH level also increased but not significantly. Histopathological examination showed inhibition of spermatogenesis evidenced by preferential loss of matured and elongated spermatids. Results of this study showed that GTE at relatively high dose may cause impairment of both the morphological and normal functional status of testis in rodents and thus its consumption at relatively high doses raises concern on male reproductive function in spite of its other beneficial effects.en_US
dc.language.isoen_USen_US
dc.publisherNISCAIR-CSIR, Indiaen_US
dc.rights CC Attribution-Noncommercial-No Derivative Works 2.5 Indiaen_US
dc.sourceIJEB Vol.49(09) [September 2011]en_US
dc.subjectFSHen_US
dc.subjectGreen teaen_US
dc.subjectLHen_US
dc.subjectSperm counten_US
dc.subjectTesticular ∆5-3-HSDen_US
dc.subjectTesticular 17-HSDen_US
dc.subjectTestosteroneen_US
dc.titleEffect of green tea (Camellia sinensis L.) extract on morphological and functional changes in adult male gonads of albino ratsen_US
dc.typeArticleen_US
Appears in Collections:IJEB Vol.49(09) [September 2011]

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