Acute toxicity evaluation of some Unani drugs in crude and processed forms

Abstract

Acute oral toxicity studies on the suspension of some Unani drugs <i style="">Azaraqi</i> (<i>Strychnos nux-vomica </i>Linn<i>.</i>) and <i style="">Sammulfar</i> (Arsenious oxide) were carried out on mice and compared to detoxified form. The effect of detoxifying process was assessed on the maximum tolerance dose of the test drugs gets affected during the treatment process. From the experimental studies it was evident that the LD-50 in detoxified form of both the test drugs found greater than crude materials.