Synthesis, characterization and biological evaluation of allyl, benzyl and 4-nitrobenzyl derivatives of aminopyridinium bromides

Abstract

A new series of allyl, benzyl and 4-nitrobenzyl derivatives of aminopyridiniumbromides have been synthesized and characterized by UV-Vis, IR and ¹H NMR spectra. The antimicrobial activity of these compounds have been evaluated <i style="">invitro</i> against <i>S. aureus</i>, <i>P. murabilis</i>,<i> E. coli</i>, <i>C. albicans</i>,<i> A. niger </i>by disc diffusion method. All the microorganisms tested are found to be sensitive to the test compounds except N-allyl–3–aminopyridiniumbromide which is hygroscopic at room temperature.