Please use this identifier to cite or link to this item:
http://nopr.niscpr.res.in/handle/123456789/14158| Title: | Sustained stomach specific delivery of piroxicam from floating emulsion polyelectrolyte complex beads |
| Authors: | Verma, Anurag Dixit, Raghav Pandit, Jayant K |
| Keywords: | Chitosan;Emulsion PEC beads;Floating drug delivery;Gelucire;Piroxicam |
| Issue Date: | Jun-2012 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | This study presents development of floating emulsion polyelectrolyte complex (PEC) beads based on gellan-chitosan PEC and Gelucire 39/01 and 50/13 without using any chemical crosslinker, and release from developed beads of piroxicam (PRM) in 0.1 M HCl (pH 1.2). Developed beads showed excellent buoyancy, significantly improved encapsulation efficiency and sustained release of PRM compared to floating gellan-chitosan beads bearing PRM. Thus emulsion PEC beads may form a potential stomach site specific drug delivery system for PRM delivery. |
| Page(s): | 407-412 |
| ISSN: | 0975-1084 (Online); 0022-4456 (Print) |
| Appears in Collections: | JSIR Vol.71(06) [June 2012] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| JSIR 71(6) 407-412.pdf | 281.96 kB | Adobe PDF | View/Open |
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