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http://nopr.niscpr.res.in/handle/123456789/15193| Title: | Acid catalyzed condensation of pyroglutamic acid with arylaldehydes: Synthesis of (3R, 7aS)-3-aryldihydropyrrolo[1, 2-c] oxazol-1, 5(3H, 6H) dione |
| Authors: | Prasad, Jagdish Panday, Sharad Kumar |
| Keywords: | Pyroglutamic acid;Aromatic aldehyde;Acid catalyzed condensation reaction;Bicyclic derivative |
| Issue Date: | Dec-2012 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | A simple strategy for the synthesis of (3R, 7aS)-3-aryldihydropyrrolo [1, 2-c] oxazol-1, 5(3H, 6H)-diones as bicyclic hemiaminals through acid catalyzed condensation of pyroglutamic acid with arylaldehydes has been described. This could be useful for the synthesis of complex natural products requiring α-substitution in proline or pyroglutamate skeleton. |
| Page(s): | 1781-1784 |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Appears in Collections: | IJC-B Vol.51B(12) December 2012] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCB 51B(12) 1781-1784.pdf | 81.44 kB | Adobe PDF | View/Open |
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