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http://nopr.niscpr.res.in/handle/123456789/15200| Title: | An efficient synthesis of lactarochromal from 6-amino-2,2-dimethylchroman-4-one |
| Authors: | Kamat, Vijayendra P Asolkar, Ratnakar N Kirtany, Janardan K |
| Keywords: | Lactarochromal;Lactarius deliciosus;6-amino-2,2- dimethylchroman-4-one;6-iodo-2,2-dimethylchroman-4-one;N- formylpiperidine |
| Issue Date: | Dec-2012 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | Lactarochromal 1, a metabolite of Lactarius deliciosus, has been synthesised starting from 6-amino-2,2-dimethylchroman-4-one 3, which in turn, is prepared from paracetamol via the known intermediates. The amino compound 3 is then converted to the iodo compound 4, followed by formylation of the latter using N-formylpiperidine to provide, efficiently, the natural product 1 in good yield. |
| Page(s): | 1761-1762 |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Appears in Collections: | IJC-B Vol.51B(12) December 2012] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCB 51B(12) 1761-1762.pdf | 48.34 kB | Adobe PDF | View/Open |
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