Please use this identifier to cite or link to this item: http://nopr.niscpr.res.in/handle/123456789/15291
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dc.contributor.authorBansal, Geetanjali-
dc.contributor.authorSingh, Uma-
dc.contributor.authorBansal, M P-
dc.date.accessioned2012-12-24T18:45:32Z-
dc.date.available2012-12-24T18:45:32Z-
dc.date.issued2001-06-
dc.identifier.issn0975-0959 (Online); 0301-1208 (Print)-
dc.identifier.urihttp://hdl.handle.net/123456789/15291-
dc.description176-179en_US
dc.description.abstractIncubation of murine peritoneal macrophages with 7β hydroxycholesterol (7 β -OH) for 24 hr led to dose-dependent reduction in cellular glutathione content as well as nitrite levels in the medium. Treatment with an inorganic form of selenium, sodium selenite which is a potent antioxidant, elevated the cellular glutathione levels and decreased nitrite levels. Our results suggest that 7 β -OH may exert its pro-atherogenic effect by inhibiting glutathione synthesis and nitric oxide production by macrophages present in the arterial wall and thus, impair the cellular antioxidant defense systemen_US
dc.language.isoen_USen_US
dc.publisherNISCAIR-CSIR, Indiaen_US
dc.rights CC Attribution-Noncommercial-No Derivative Works 2.5 Indiaen_US
dc.sourceIJBB Vol.38(3) [June 2001]en_US
dc.titleInfluence of 7β-hydroxycholesterol on glutathione status and nitric oxide production in macrophages: In vitro studies en_US
dc.typeArticleen_US
Appears in Collections:IJBB Vol.38(3) [June 2001]

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