Please use this identifier to cite or link to this item:
http://nopr.niscpr.res.in/handle/123456789/15302| Title: | Purification and characterization of receptors for myoinositol trisphosphate and myoinositol tetrakis phosphate from Entamoeba histolytica |
| Authors: | Giri, Banabehari Das, Ruma Raha, Sanghamitra Biswas, Susweta |
| Issue Date: | Aug-2001 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | The microsomal fraction from the log phase of Entamoeba histolytica cells contains Ins(1,4,5)P3 and Ins(1 ,3,4,5)P4 binding activity. The binding proteins/receptors for both Ins(1,4,5)P3 and Ins(1,3,4,5)P4 were purified and found to be specific for each ligand. The molecular masses for native proteins for InsP3 and Ins P4 are 138 kDa and 130 kDa respectively having subunits of 69 kDa and 64 kDa respectively. That these proteins are associated with Ca2+ release was confirmed by including these proteins separately in proteoliposomes and adding Ins P3 and Ins P4 in both the cases. |
| Page(s): | 253-257 |
| ISSN: | 0975-0959 (Online); 0301-1208 (Print) |
| Appears in Collections: | IJBB Vol.38(4) [August 2001] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJBB 38(4) 253-257.pdf | 1.05 MB | Adobe PDF | View/Open |
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