Please use this identifier to cite or link to this item:
http://nopr.niscpr.res.in/handle/123456789/15311| Title: | Polyunsaturated fatty acids (PUFA) regulate neurotransmitter contents in rat brain |
| Authors: | Varghese, Sheelu Shameena, Bake Lakshmy, P S Biju, M P Shankar, Easwar PN Paulose, C S Oommen, V Oommen |
| Issue Date: | Oct-2001 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | The effects of feeding of 6-propylthiouracil (6-PTU) and polyunsaturated fatty acids (PUFA) independently and in combination and administration (ip) of a single dose of triiodothyronine (T3) (2.5μg/l00g body wt) along with feeding of 6-PTU and PUFA were studied in rat brain. Dopamine (DA), 5-hydroxytryptophan (5-HTP), seroton in (5-HT), 5-hydroxy in dole acetic acid (5-HIAA), norepinephrine (NE) and epinephrine (EPI) contents were assayed in the hypothalamus and cerebral cortex regions. It was found that 6-PTU feeding resulted in decrease in dopamine, 5-HT, 5-HTP and 5-HIAA in both regions. In animals fed with PUFA followed by administration of T3, the DA level was found normal. |
| Page(s): | 327-330 |
| ISSN: | 0975-0959 (Online); 0301-1208 (Print) |
| Appears in Collections: | IJBB Vol.38(5) [October 2001] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJBB 38(5) 327-330.pdf | 1.02 MB | Adobe PDF | View/Open |
Items in NOPR are protected by copyright, with all rights reserved, unless otherwise indicated.