<span style="font-size:11.0pt;font-family: "Times New Roman";mso-fareast-font-family:"Times New Roman";mso-bidi-font-family: Mangal;mso-ansi-language:EN-GB;mso-fareast-language:EN-US;mso-bidi-language: HI" lang="EN-GB">Phylogenetic analysis and biological activity of <i style="mso-bidi-font-style: normal">Streptomyces </i>sp. CIMAP-A₂ isolated from industrially polluted soil</span>

Abstract

A new strain of <i style="mso-bidi-font-style: normal">Streptomyces</i> was isolated from heavy metal polluted soil of industrial (tannery) area of Jajmau, Kanpur, India. The strain was designated as<i style="mso-bidi-font-style:normal"> Streptomyces </i><span style="mso-bidi-font-style:italic">sp. CIMAP A₂ based on cultural, morphological and physiological studies<span style="mso-bidi-font-style: italic">. Further, molecular characterization of the strain was carried out based on sequencing 1520 bp fragment of 16s rRNA amplicon, which validated it as <i style="mso-bidi-font-style:normal">Streptomyces</i> species (MTCC 10489). The strain was found to be antagonistic to different human pathogenic bacteria as well as phytopathogenic fungi in dual plate assay. It produced hydroxamate siderophore, which was highly effective in making complexes with the trace elements like Fe³⁺, Sn²⁺, Mn^2+, Pb²⁺and Zn²⁺. The studies indicate that the strain is a new species of <i>Streptomyces</i> with broad spectrum of antibacterial and antifungal activities.

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