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http://nopr.niscpr.res.in/handle/123456789/15690| Title: | In silico analysis reveals the role of horizontally transferred genes (HGTs) in shaping the pathogenicity of Xanthomonas |
| Authors: | Kundu, Shrabanti Bothra, Asim Tisa, Louis S Sen, Arnab |
| Keywords: | Codon adaptation index;Codon usage;Correspondence analysis;Horizontally transferred genes;Pathogenicity;Xanthomonas |
| Issue Date: | Oct-2012 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | The role of Xanthomonas spp. as phytopathogen has been well recognized in diseases of important crops like rice, canola, tomato, citrus, etc. The genomes of a number of Xanthomonas strains are also fully sequenced and they are made available in various data bases. In the present study, in silico analysis of six Xanthomonas genomes was carried out. Synonymous codon usage pattern study in these genomes revealed that pathogenicity related (PR)-horizontally transferred genes (HGTs) were, in general, expressed lowly and were less biased in comparison with average protein coding genes and ribosomal protein genes. Moreover, the correspondence analysis showed that the ribosomal genes were clustered at one end, while the HGTs and the PR-HGTs were all scattered. It has been also revealed that how the virulent HGTs, in spite of having low expression levels, did enhance the pathogenicity of the Xanthomonas strains to certain extent by targeting important cellular functions. |
| Page(s): | 404-411 |
| ISSN: | 0975-0967 (Online); 0972-5849 (Print) |
| Appears in Collections: | IJBT Vol.11(4) [October 2012] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJBT 11(4) 404-411.pdf | 412.25 kB | Adobe PDF | View/Open |
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