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http://nopr.niscpr.res.in/handle/123456789/15901| Title: | A reinvestigation of reaction of 2-hydrazino-3-phenylquinoxaline with 1,3-diketones: Synthesis and characterization of regioisomeric 1-(3'-phenylquinoxalin-2'-yl)-3,5-disubstitutedpyrazoles and 1,2,4-triazolo[4,3-a]quinoxalines |
| Authors: | Eakta Aggarwal, Ranjana Sumran, Garima |
| Keywords: | 2-Hydrazino-3-phenylquinoxaline;Minimum energy diagrams;NMR studies;Regioisomeric 1-(3'-phenyl¬quinoxalin-2'-yl)-3,5-disubstitutedpyrazoles;1,2,4-triazolo[4,3-a]quinoxaline |
| Issue Date: | Feb-2013 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | A reinvestigation into the reaction of 2-hydrazino-3-phenylquinoxaline 1 with several 1,3-diketones 2a-g reveals that a mixture of regioisomeric 1-(3'-phenylquinoxalin-2'-yl)-3,5-disubstitutedpyrazoles 3a-g and 4a-e and 1-methyl-4-phenyl/methyl-1,2,4-triazolo[4,3-a]quinoxalines 5a,b is formed as reaction products rather than erroneously reported exclusive formation of triazole 5 in case of aryl alkyl-1,3-diketones or 1-(3'-phenylquinoxalin-2'-yl)-3-alkylpyrazoles 4 in case of dialkyl and diaryl-1,3-diketones. Structural elucidation of the regioisomeric pyrazoles has been established by the spectroscopic data (1H, 13C NMR, COSY experiments and HRMS) and minimum energy 3-D diagrams. |
| Page(s): | 273-281 |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Appears in Collections: | IJC-B Vol.52B(02) [February 2013] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCB 52B(2) 273-281.pdf | 183.74 kB | Adobe PDF | View/Open |
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