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  5. IJC-A Vol.52A [2013]
  6. IJC-A Vol.52A(02) [February 2013]
Please use this identifier to cite or link to this item: http://nopr.niscpr.res.in/handle/123456789/15920
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dc.contributor.authorJenita, M Jude-
dc.contributor.authorVenkatesh, G-
dc.contributor.authorSubramanian, V K-
dc.contributor.authorRajendiran, N-
dc.date.accessioned2013-02-06T09:03:27Z-
dc.date.available2013-02-06T09:03:27Z-
dc.date.issued2013-02-06T09:03:27Z-
dc.identifier.issn0975-0975(Online); 0376-4710(Print)-
dc.identifier.urihttp://hdl.handle.net/123456789/15920-
dc.description207-216en_US
dc.description.abstractThe inclusion complexation behavior of three antihypertensive drugs, viz., salbutamol, sotalol and atenolol with hydroxypropyl-α-cyclodextrin (HP-α-CD) and hydroxypropyl-β-cyclodextrin (HP-β-CD) is investigated by UV-visible, steady state/time resolved fluorescence and PM3 methods and compared with complexation with α-CD and β-CD. In the presence of any of the CDs, dual emission is observed in these drugs, whereas in the absence of CDs, single emission is seen. Addition of CD to aqueous solutions of the drugs results in excimer emission. In CD solutions, the monomer emission intensity decreases regularly while excimer emission intensity increases. The excimer emission is concluded to be due to a 1:2 inclusion complex between the CD and the drugs. en_US
dc.language.isoen_USen_US
dc.rights CC Attribution-Noncommercial-No Derivative Works 2.5 Indiaen_US
dc.sourceIJC-A Vol.52A(02) [February 2013]en_US
dc.subjectExcimer formationen_US
dc.subjectInclusion complexesen_US
dc.subjectEncapsulationen_US
dc.subjectMolecular modelingen_US
dc.subjectFluorescence spectraen_US
dc.subjectAntihypertensive drugsen_US
dc.subjectDrug deliveryen_US
dc.subjectSalbutamolen_US
dc.subjectSotalolen_US
dc.subjectAtenololen_US
dc.subjectCyclodextrinsen_US
dc.subjectOligosaccharidesen_US
dc.titleExcimer formation in inclusion complexes of antihypertensive drugs with HP-α- and HP-β-cyclodextrinsen_US
dc.typeArticleen_US
Appears in Collections:IJC-A Vol.52A(02) [February 2013]

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