Sonic hedgehog inhibition induces mouse embryonic stem cells to differentiate toward definitive endoderm

Ghanbari, Ali; Khazaei, Mozafar; Hashemi-Tabar, Mahmoud; Rabzia, Arezou; Fathi, Fardin; Bayat, Parvin-Dokht

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Please use this identifier to cite or link to this item: http://nopr.niscpr.res.in/handle/123456789/16127

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DC Field	Value	Language
dc.contributor.author	Ghanbari, Ali	-
dc.contributor.author	Khazaei, Mozafar	-
dc.contributor.author	Hashemi-Tabar, Mahmoud	-
dc.contributor.author	Rabzia, Arezou	-
dc.contributor.author	Fathi, Fardin	-
dc.contributor.author	Bayat, Parvin-Dokht	-
dc.date.accessioned	2013-02-28T03:47:57Z	-
dc.date.available	2013-02-28T03:47:57Z	-
dc.date.issued	2013-03	-
dc.identifier.issn	0975-1009 (Online); 0019-5189 (Print)	-
dc.identifier.uri	http://hdl.handle.net/123456789/16127	-
dc.description	201-207	en_US
dc.description.abstract	In the experimental group (shh inhibited group), there were significant decreases in the expression of Oct4, Nanog, Shh, GATA4, Brachyury and Goosecoid, while increases were observed for TAT and Pdx1. The expression of Sox17 did not differ between two control and experimental groups. In experimental group, the amount of GSC positive cells was somehow lower but it seems that there was no difference for Sox17. Shh inhibition induces ESCs to differentiate toward definitive endoderm by committing mesendodermal lineages.	en_US
dc.language.iso	en_US	en_US
dc.publisher	NISCAIR-CSIR, India	en_US
dc.rights	CC Attribution-Noncommercial-No Derivative Works 2.5 India	en_US
dc.source	IJEB Vol.51(03) [March 2013]	en_US
dc.subject	Definitive endoderm	en_US
dc.subject	Dithizone	en_US
dc.subject	Hedgehog interacting protein	en_US
dc.subject	Mesendoderm	en_US
dc.subject	Mouse embryonic stem cell	en_US
dc.title	Sonic hedgehog inhibition induces mouse embryonic stem cells to differentiate toward definitive endoderm	en_US
dc.type	Article	en_US
Appears in Collections:	IJEB Vol.51(03) [March 2013]

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