Please use this identifier to cite or link to this item: http://nopr.niscpr.res.in/handle/123456789/16185
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dc.contributor.authorPatil, Renukadevi-
dc.contributor.authorBiradar, J S-
dc.date.accessioned2013-03-03T20:31:42Z-
dc.date.available2013-03-03T20:31:42Z-
dc.date.issued1999-01-
dc.identifier.urihttp://hdl.handle.net/123456789/16185-
dc.description76-82en_US
dc.description.abstract3,5-Disubstituted indole-2-carboxylates 1 a-g are reacted with hydrazine hydrate to furnish the corresponding indole-2-carboxyhydrazides 2a-g These on reaction with alkaline carbon disulphide under thermal reaction  conditions produce respective 2-(5'-thioxo-1',3',4'-oxadiazol-2'-yl) indoles 3a-g. Reaction of 3a-g with ethyl chloroacetate and alkyl halides in dry acetone and anhyd, K2CO3 yield indoles 4a-g and 6a-r, respectively. Compounds 4a-g on further reaction with hydrazine hydrate in ethanol afforded the compounds 5a-g. Compounds synthesised have been screened for their biological activities.en_US
dc.language.isoen_USen_US
dc.publisherNISCAIR-CSIR, Indiaen_US
dc.rights CC Attribution-Noncommercial-No Derivative Works 2.5 Indiaen_US
dc.sourceIJC-B Vol.38B(01) [January 1999]en_US
dc.titleSynthesis and biological activities of new 3,5-disubstituted -2-( ethyl-5'-thioxo-1',3',4'-oxadiazol-4'-ethylacetate-2'-yl)indoles,-2-(5'- thioxo-1',3',4'-oxadiazol-4'methylcarboxyhydrazide-2'-yl) indoles and -2-(5'- thioxo-1',3', 4'-oxadiazol-4'alkyl- 2'-yl) indolesen_US
dc.typeArticleen_US
Appears in Collections:IJC-B Vol.38B(01) [January 1999]

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