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http://nopr.niscpr.res.in/handle/123456789/16257| Title: | Synthesis, characterisation and anthelmintic activity of 3-(4-acetyl-5-phenyl-4,5-dihydro-1,3,4-oxadiazol-2-yl)- 2H-chromen-2-one derivatives |
| Authors: | Sudha, B Naga Sridhar, C Sastry, V Girija Reddy, Y S R Sreevidya, Owk Lavanya, S Jyothi, V Asha Nagesh, V Sen, Saikat Chakraborty, Raja |
| Keywords: | Oxadiazole;Coumarin;Anthelmintic activity |
| Issue Date: | Mar-2013 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | Convectional synthesis of several coumarin-oxadiazole derivatives from starting compounds 2-hydroxy benzaldehyde and diethylmalonate has been accomplished. Successful synthesis of the derivatives has been confirmed by spectral studies i.e. UV, IR, MS and 1H NMR. All successfully synthesized compounds have been screened for in vitro anthelmintic activity by taking adult Indian earthworms Pheretima posthuma. Among all the derivatives 4-chloro derivatives have shown maximum activity when compared with the standard. |
| Page(s): | 422-427 |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Appears in Collections: | IJC-B Vol.52B(03) [March 2013] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCB 52B(3) 422-427.pdf | 69.79 kB | Adobe PDF | View/Open |
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