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http://nopr.niscpr.res.in/handle/123456789/16439| Title: | Synthesis of 7-hydroxy-6,8-di-C-prenylflavanone |
| Authors: | Hossain, M Amzad Salehuddin, S M |
| Issue Date: | May-1999 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | The synthesis of flavanone A 8, a constituent of the leaves and bark of Milletia ovalifolia is described. β-Resacetophenone 1 on treatment with methoxymethyl chloride afford 2,4-dimethoxymcthoxyacctophenone 2 which on nuclear prenylation yield 2,4- dimethoxymcthoxy-3 ,5-di-C-prenylacetophenone 5. Alkaline condensation of 5 with benzaldehyde give 2',4'-dimethoxymethox y-3',5' -di-C-prenylchalcone 6. 2',4'-Dihydroxy-3',5'-di–C-prenylchalcone 7 obtained by the demethoxymethylation of 6, on treatment with NaOAc/EtOH furnish 7-hydroxy-6,8-di-C-prenylflavanone (8, flavanone A). |
| Page(s): | 593-595 |
| Appears in Collections: | IJC-B Vol.38B(05) [May 1999] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCB 38B(5) 593-595.pdf | 689.99 kB | Adobe PDF | View/Open |
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