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http://nopr.niscpr.res.in/handle/123456789/16442| Title: | Synthesis of 5,7,4'-trihydroxy-6-C-prenylflavone |
| Authors: | Hossain, M Amzad |
| Issue Date: | May-1999 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | 5,7,4'-Trihydroxy-6-C-prenylflavone 6 isolated from the fruits of Maclura pomifera has been synthesized by the following route. Phloroacetophenone 1 on treatment with methoxymethyl chloride afford 2-hydroxy-4,6-di(methoxymethoxy) acetophenone 2 which on nuclear prenylation yield 2-hydroxy-4,6-di(methoxymethoxy)-5-C-prenylacetophenone 3 and several other minor products. The methoxymethylated product 3 on condensation with p-hyd roxybenzaldehyde gives the chalcone 4. DDQ (2,3 –dichloro-5, 6-dicyano-1,4-benzoquinone) treatment of 4 afford the compound 5 which upon demethoxymethylation furnish the title compound 6. |
| Page(s): | 590-592 |
| Appears in Collections: | IJC-B Vol.38B(05) [May 1999] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCB 38B(5) 590-592.pdf | 627.69 kB | Adobe PDF | View/Open |
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