Synthesis and reactions of some new 5-aryl-3-oxo-7 -(4'-aryl-2' ,5 '-dioxo-1', 2' ,3 ', 4'-tetrahydrofluoren-3'-yl)-5H, 8H-2,3- dihydrothiazolo[5,4-b]pyrimidines of expected biological activity

Salama, M A; EI-Essa, S A

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Please use this identifier to cite or link to this item: http://nopr.niscpr.res.in/handle/123456789/16475

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DC Field	Value	Language
dc.contributor.author	Salama, M A	-
dc.contributor.author	EI-Essa, S A	-
dc.date.accessioned	2013-03-24T13:18:58Z	-
dc.date.available	2013-03-24T13:18:58Z	-
dc.date.issued	1999-06	-
dc.identifier.uri	http://hdl.handle.net/123456789/16475	-
dc.description	739-742	en_US
dc.description.abstract	2-Arylidene-indane-1,3-dione 1 on treatment with acetyl acetone in gl. acetic acid gives 3-acetyl-4-aryl-2,5-dioxo-1,2,3,4- tetrahydrofluorenes 2a-d which on reaction with benzaldehyde yield 4-aryl-3-cinnamoyl-2, 5-dioxo-1, 2, 3, 4-tetrahydrofluorenes 3a-d. Compounds 3a-d when reacted with thiourea in gl. CH₃COOH/Ac₂O in the presence of anhyd. sodium acetate afford 4,5-diaryl-6-(4'-aryl-2', 5' -dioxo-1', 2', 3', 4'-tetrahydrofluoren- 3'-yl)-1, 2, 3, 4-tetrahydropyrimidine-2-thiones 4a-d which on treatment with chloroacetic acid furnish 5-aryl-3-oxo-7-(4'-aryl- 2', 5' -dioxo-1',2',3',4' -tetrahydrofluoren-3'-yl)-5H, 8H-2,3-dihydrothi azolo[5,4-b]pyrimidines 5a-d. Compounds 5a-d on condensation with benzaldehyde yield 2-arylmethylene-3-oxo-Sphenyl-7-(4' -aryl-2', 5' -dioxo-1', 2', 3', 4'-tetrahydrotluoren-3'yl)-5H, 8H-2,3-dihydrothiazolo[5,4- b ]pyrimidines 6a-d.	en_US
dc.language.iso	en_US	en_US
dc.publisher	NISCAIR-CSIR, India	en_US
dc.rights	CC Attribution-Noncommercial-No Derivative Works 2.5 India	en_US
dc.source	IJC-B Vol.38B(06) [June 1999]	en_US
dc.title	Synthesis and reactions of some new 5-aryl-3-oxo-7 -(4'-aryl-2' ,5 '-dioxo-1', 2' ,3 ', 4'-tetrahydrofluoren-3'-yl)-5H, 8H-2,3- dihydrothiazolo[5,4-b]pyrimidines of expected biological activity	en_US
dc.type	Article	en_US
Appears in Collections:	IJC-B Vol.38B(06) [June 1999]

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