<span style="font-size:12.0pt;font-family: "Times New Roman";mso-fareast-font-family:"Times New Roman";mso-ansi-language: EN-IN;mso-fareast-language:EN-IN;mso-bidi-language:AR-SA" lang="EN-IN">Some reactions of 2-phenyl-4(3<i style="mso-bidi-font-style:normal">H</i>)-quinazolinones</span>

Abdo, Mohamed A; Zeid, Ibrahim F; EI-Hiti, Gamal A; Mahmoud, Olfat E

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DC Field	Value	Language
dc.contributor.author	Abdo, Mohamed A	-
dc.contributor.author	Zeid, Ibrahim F	-
dc.contributor.author	EI-Hiti, Gamal A	-
dc.contributor.author	Mahmoud, Olfat E	-
dc.date.accessioned	2013-03-27T19:44:07Z	-
dc.date.available	2013-03-27T19:44:07Z	-
dc.date.issued	1999-07	-
dc.identifier.uri	http://hdl.handle.net/123456789/16503	-
dc.description	850-853	en_US
dc.description.abstract	Reaction of 2-phenyl-3, 1-benzoxazin-4H-one 1 with thiocarbohydrazide in refluxing ethanol affords 2-phenyl-3- thiosemicarbazido-4(3H)-quinazolinone 2. However, thioxotetrazinoquinazo line 3 is obtained in 79% isolated yield when the reaction mixture is fused in an oil bath at 160°C. Compound 3 is also obtained when compound 2 is heated in an oil bath at 170°C. On the other hand , compound 3 reacts with paraformaldehyde and secondary amines to afford the corresponding quinazoline derivatives 4 and 5. The diazonium salt of 3-amino-2-phenyl- 4(3H)-quinazolinone 6 reacts with some active methylene compounds (diethyl malonate, ethyl acetoacetate, malononitrile and acetyl acetone) to affords the quinazolinone derivatives 8-11 in good yields. Reactions of 8 with hydrazine hydrate and phenyl hydrazine afford the corresponding pyrazolonoquinazolinones 12 and 13, respectively. Reaction of 8 with urea furnishes pyrimidinoquinazolinones 14 in 79% isolated yield. However, reaction of 11 with hydrazine hydrate gives pyrazoloquinazolinones 15 in 83% isolated yield.	en_US
dc.language.iso	en_US	en_US
dc.publisher	NISCAIR-CSIR, India	en_US
dc.rights	CC Attribution-Noncommercial-No Derivative Works 2.5 India	en_US
dc.source	IJC-B Vol.38B(07) [July 1999]	en_US
dc.title	Some reactions of 2-phenyl-4(3H)-quinazolinones	en_US
dc.type	Article	en_US
Appears in Collections:	IJC-B Vol.38B(07) [July 1999]

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