Please use this identifier to cite or link to this item: http://nopr.niscpr.res.in/handle/123456789/16567
Title: Studies on anti-inflammatory drugs of 2- arylpropanoic acids: Part IX1 - A practical synthesis of ketoprofen by 1,2-aryl rearrangement
Authors: Chen, Fener
Liu, Jidong
Shao, Lanying
Yan, Qiongjiao
Issue Date: Aug-1999
Publisher: NISCAIR-CSIR, India
Abstract: An efficient synthesis of ketoprofen via chloration, Friedel-Crafts acylation, reduction, coupling, ketalization, rearrangement, hydrolysis and oxidation from commercially available m-bromo- benzoic acid in overall yield of about 60% has been described.
Page(s): 989-992
Appears in Collections:IJC-B Vol.38B(08) [August 1999]

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