Please use this identifier to cite or link to this item:
http://nopr.niscpr.res.in/handle/123456789/16572| Title: | An efficient method to chiral β-hydroxy acids: Synthesis of lipid-A side chain |
| Authors: | Nandanan, E Phukan, Prodeep Sudalai, A |
| Issue Date: | Aug-1999 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | The synthesis of optically active β-hydroxy acids 5a-c is achieved in four steps from their corresponding terminal olefins 1a-c by employing Sharpless asymmetric dihydroxylation. The regioselective ring opening of chiral cyclic sulfites 3a-c with cyanide ion, constitutes the key reaction, thus producing the hydroxy nitriles 4a-c. |
| Page(s): | 893-896 |
| Appears in Collections: | IJC-B Vol.38B(08) [August 1999] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCB 38B(8) 893-896.pdf | 885.25 kB | Adobe PDF | View/Open |
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