Please use this identifier to cite or link to this item:
http://nopr.niscpr.res.in/handle/123456789/16611| Title: | Microwave-induced synthesis of nitrogen-mustard derivatives |
| Authors: | Kidwai, Mazaahir Kumar, Rajesh Kohli, Seema |
| Issue Date: | Sep-1999 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | N,N-Bis (2-hydroxyethyl) amino substituted propiophenones 2a-c have been prepared using Mannich reaction from substituted acetophenones 1a-c. 2a-c on hydrazinolysis yield 3a-f which on chlorination give nitrogen mustards 4a-f. 4a-f on reaction with chloracetyl chloride, N-methylmorpholine and chlorobenzene under mircrowave activation (MWI) afford β-lactams 5a-f while cyclisation of 4a-f with polyphosphoric acid under MWI give the indoles 6a-f. |
| Page(s): | 1132-1135 |
| Appears in Collections: | IJC-B Vol.38B(09) [September 1999] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCB 38B(9) 1132-1135.pdf | 716.55 kB | Adobe PDF | View/Open |
Items in NOPR are protected by copyright, with all rights reserved, unless otherwise indicated.