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http://nopr.niscpr.res.in/handle/123456789/16634| Title: | Synthesis and antimicrobial activity of new 1-n-butyl-3-acetyl-5-(2,4-diamino-1,3,5-triazin-6-yl)methoxy-2-methylindole derivatives |
| Authors: | Gadaginamath, G S Kavali, R R Pujar, S R |
| Issue Date: | Oct-1999 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | 5-Hydroxyindole 1a is reacted with bromine in acetic acid to yield 6-bromo-5-hydroxyindole 1b. Compounds 1a-b are condensed with chloroacetonitrile in refluxing acetone in the presence of K2CO3 to obtain 3-acetyl-1-n-butyl-2-methylindol-5-yloxyacetonitriles 2a-b which are then reacted with dicyanodiamide in the presence of KOH in methanol and isopropanol to obtain the required 1-n-butyl-3-acetyl-5-(2,4-diamino-1,3,5-triazin-6-yl)methoxy-2-methylindoles 3a-b. All these new compounds have been screened for their antibacterial and antifungal activities. |
| Page(s): | 1226-1228 |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Appears in Collections: | IJC-B Vol.38B(10) [October 1999] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCB 38B(10) 1226-1228.pdf | 617.88 kB | Adobe PDF | View/Open |
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