Please use this identifier to cite or link to this item:
http://nopr.niscpr.res.in/handle/123456789/16731| Title: | Selective monofluorination : mechanistic studies and synthetic applilcations |
| Authors: | GREE, Rene |
| Issue Date: | Sep-2000 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | The introduction of fluorine into organic molecules is an important tool in modifying their physical, chemical and biological properties. This review briefly presents the different approaches which can be used for selective monofluorination. The strategies that we have developed for fluorination vicinal to unsaturated systems, paying attention to the regio-and stereo-control during the fluorination step are then discussed in detail. From these studies, two promising approaches emerge: the first employs transition metal complexes; the second uses tailor made fluorinated key building blocks. Some applications to the preparation of natural product analogues are also mentioned. |
| Page(s): | 646-673 |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Appears in Collections: | IJC-B Vol.39B(09) [September 2000] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCB 39B(9) 646-673.pdf | 4.67 MB | Adobe PDF | View/Open |
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