Please use this identifier to cite or link to this item:
http://nopr.niscpr.res.in/handle/123456789/17715| Title: | Development and Evaluation of Matrix and Two Layered Sustained Release Suppositories of Nimesulide |
| Authors: | Ravi, M Sa, B Bandyopadhyay, A K |
| Issue Date: | May-2002 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | Nimesulide loaded conventional suppositories, sustained release matrix suppositories and sustained realesed two layered suppositories were prepared using polyethyleneglycol (PEG) -4000 and ethylcellulose. In vitro characteristics of these suppositories were evaluated. In comparison to conventional suppositories the release of drug from sustained release matrix suppositories was gradual and extended over a period of time. On the other hand, two layered suppositories produced an initial quick release followed by ex tended release of drug. |
| Page(s): | 366-369 |
| ISSN: | 0975-1084 (Online); 0022-4456 (Print) |
| Appears in Collections: | JSIR Vol.61(05) [May 2002] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| JSIR 61(5) 366-369.pdf | 702.13 kB | Adobe PDF | View/Open |
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