Kinetics of substitution of aqua ligands from cis-diaqua (ethylenediamine)platinum(II) perchlorate by guanosine in aqueous medium

Sengupta, Partha S; Sinha, Ramanath; Bera, Sujit K; De, Gauri S

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Please use this identifier to cite or link to this item: http://nopr.niscpr.res.in/handle/123456789/18246

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DC Field	Value	Language
dc.contributor.author	Sengupta, Partha S	-
dc.contributor.author	Sinha, Ramanath	-
dc.contributor.author	Bera, Sujit K	-
dc.contributor.author	De, Gauri S	-
dc.date.accessioned	2013-05-20T06:55:34Z	-
dc.date.available	2013-05-20T06:55:34Z	-
dc.date.issued	2002-04	-
dc.identifier.issn	0975-0975(Online); 0376-4710(Print)	-
dc.identifier.uri	http://hdl.handle.net/123456789/18246	-
dc.description	712-717	en_US
dc.description.abstract	The kinetics of the interaction of guanosine with cis-[Pt(en)(H₂O)₂]²⁺ + have been studied spectrophotometrically as a Function of [Pt(en)(H₂O)₂²⁺], [guanosine] and temperature at pH 4.0 where the substrate complex exists predominantly as the diaqua species. Base stacking and metal induced macrochelate formation of guanosine plays a vital role in determining the concentration limit of guanosine during kinetics. Substitution occurs in two consecutive steps; both dependent on the guanosine concentration. Activation parameters for both steps have been calculated. The low ∆H₁^# (36.28 ± 0.5 kJ mol^-1) and large negative values of ∆S₁^#(- 125.3 ± 1.5 J K^-1 mol^-1) as well as ∆H₂^# (36.03 ± 0.6 kJ mol^-1) and ∆S₂^# (-149.2 ± 1.9 J K^-1 mol^-1) indicate associative modes of activation for both the ligand substitution processes ill the two consecutive steps.	en_US
dc.language.iso	en_US	en_US
dc.publisher	NISCAIR-CSIR, India	en_US
dc.rights	CC Attribution-Noncommercial-No Derivative Works 2.5 India	en_US
dc.source	IJC-A Vol.41A(04) [April 2002]	en_US
dc.title	Kinetics of substitution of aqua ligands from cis-diaqua (ethylenediamine)platinum(II) perchlorate by guanosine in aqueous medium	en_US
dc.type	Article	en_US
Appears in Collections:	IJC-A Vol.41A(04) [April 2002]

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