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http://nopr.niscpr.res.in/handle/123456789/18396| Title: | Interaction of zinc with cysteinylglycine and histidine containing di-peptides : Relevance to zinc binding sites in transcription factor IIIA |
| Authors: | Reddy, P Rabindra Mohan, S Krishna |
| Issue Date: | Sep-2002 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | The interaction of zinc with dipeptides, histidylalanine and histidylleucine has been investigated. The binding modes and the stability factor have been determined by pH metry and 1H NMR. The interaction of Zn with these ligands in the presence of cysteinylglycine has also been investigated as a model for zinc centre in TFIIIA. The findings are that these dipeptides act as bidentate ligands both in binary and ternary mode. The coordinating sites and geometry around Zn are assigned. The conclusion from this model are in agreement with Zn binding sites in TFIIIA. |
| Page(s): | 1816-1820 |
| ISSN: | 0975-0975(Online); 0376-4710(Print) |
| Appears in Collections: | IJC-A Vol.41A(09) [September 2002] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCA 41A(9) 1816-1820.pdf | 895.34 kB | Adobe PDF | View/Open |
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