Synthesis, characterization and biological studies of some bivalent metal complexes of schiff bases derived from aminothiazole and substituted azosalicylaldehyde

Abstract

Metal complexes of the type MLX {M=Co(II), Ni(II), Cu(II), Zn(II), Cd(II) and Hg(II)) have been synthesised using 5- phenylazosalicylidene-4-phenyl-2-aminothiazole (PASPAT), 5-(<i>p</i>-chlorophenyl)-4-phenyl-2-aminothiazole (PCPASPAT) and 5-(<i>p</i>-tolulyl)-azo salicylidene-4-phenyl-2-aminothiazole

(PTASPAT). The resulting complexes have been characterized on the basis of their elemental analysis, infrared spectra, electronic spectra, magnetic susceptibilities and molar conductance measurements. The ligands act as monobasic tridentate ligands and the complexes appear to be four co-ordinate. The antibacterial activities of the ligands and their metal complexes have been

screened against <i>Escherichia coli, Bacillus substilis, Klebsiella pneumoniae, Pseudomonas aerogens, Salmonella paratyphi B., Staphylococcus aureus </i>and <i>Proteus vulgaris.</i>