Please use this identifier to cite or link to this item:
http://nopr.niscpr.res.in/handle/123456789/18990| Title: | Effect of antidiabetic compounds on glyoxalase I activity in experimental diabetic rat liver |
| Authors: | Raju, Jayadev Gupta, Dhananjay Rao, A. Ramesha Baquer, Najma Z. |
| Issue Date: | Feb-1999 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | The activity of glyoxalase I from the soluble fraction of diabetic rat liver was found to decrease as compared to the control. Sodium orthovanadate in drinking water and Trigonella foenum graecum seed powder when administered to these diabetic animals were found to reverse the activity of glyoxalase [to control values. A combination of the above two antidiabetic compounds showed a better reversal. Vanadate and Trigonella seed powder treatment separately to diabetic rats also normalized hyperglycemia together with glyoxalase I activity. A combination of vanadate and Trigonella seed powder also restored the other general parameters of the diabetic animals. |
| Page(s): | 193-195 |
| ISSN: | 0975-1009 (Online); 0019-5189 (Print) |
| Appears in Collections: | IJEB Vol.37(02) [February 1999] |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJEB 37(2) 193-195.pdf | 864.31 kB | Adobe PDF | View/Open |
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