Please use this identifier to cite or link to this item:
http://nopr.niscpr.res.in/handle/123456789/20020Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Desai, K H | - |
| dc.contributor.author | Kulkarni, A R | - |
| dc.contributor.author | Agnihotri, S A | - |
| dc.contributor.author | Gudasi, K B | - |
| dc.contributor.author | Aminabhavi, T M | - |
| dc.date.accessioned | 2013-07-23T11:19:21Z | - |
| dc.date.available | 2013-07-23T11:19:21Z | - |
| dc.date.issued | 2006-07 | - |
| dc.identifier.issn | 0975-0975(Online); 0376-4710(Print) | - |
| dc.identifier.uri | http://hdl.handle.net/123456789/20020 | - |
| dc.description | 1667-1669 | en_US |
| dc.description.abstract | Solubility enhancement of rofecoxib in water has been studied in presence of different conce ntrations of hydrophilic polymers like polyethylene glycol-4000 polyethylene glycol-6000 and polyvinylpyrrolidone (PVP- K30); surfactants like Span-20, Tween-80 and sodium lauryl sulfate (SLS): co-solvents like ethanol, propylene glycol and glycerol and small molecules like urea, mannitol and β-cyclodextrin at 310.15 K. Drug analysis has been carried out by HPLC method using UV detector at 254 nm. Drug solubility is greatly enhanced in the presence of PVP-K30, SLS, and ethanol. In the presence of small molecules, urea enhances the solubility much higher than mannitol or β-cyclodextrin. | en_US |
| dc.language.iso | en_US | en_US |
| dc.publisher | NISCAIR-CSIR, India | en_US |
| dc.relation.ispartofseries | Int. Cl.8 A61 K | en_US |
| dc.rights |  CC Attribution-Noncommercial-No Derivative Works 2.5 India | en_US |
| dc.source | IJC-A Vol.45A(07) [July 2006] | en_US |
| dc.title | Solubility enhancement of rofecoxib in water in the presence of hydrobhilic polymers, surfactants, co-solvents, and small molecules at310.15K† | en_US |
| dc.type | Article | en_US |
| Appears in Collections: | IJC-A Vol.45A(07) [July 2006] | |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| IJCA 45A(7) 1667-1669.pdf | 628.6 kB | Adobe PDF | View/Open |
Items in NOPR are protected by copyright, with all rights reserved, unless otherwise indicated.