Catalytic kinetic spectrophotometric determination of palladium(II) and its application to the determination of traces of propylthiouracil

Abstract

The catalytic-kinetic method has been proposed for the determination of palladium(II) based on its catalytic effect on the reaction of crystal violet with hypophosphite. The reaction has

been monitored spectrophotometrically at 590 nm over the range 0.071-2.850 ppm of Pd(II). The influence of reaction variables and the effect of interfering ions have been studied. The limit of detection and relative standard deviation are 0.071 ppm and 2.76%, respectively. The developed method has been applied to the determination of Pd(II) in river water and Pd-C catalyst. The proposed method has also been applied for the determination of propylthiouracil in pharmaceutical samples based on its inhibitory effect on the palladium(II)-catalyzed reaction between crystal violet and hypophosphite ions. The decrease in absorbance of crystal violet at 590 nm is proportional to 1.7-248.0 ppb of PTU. The limit of detection and RSD are 1.7 ppb and 2.53%, respectively.